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Details on Person p-T497,T638,S657-PRKCA [cytosol]

Class:Id	EntityWithAccessionedSequence:4332337
_displayName	p-T497,T638,S657-PRKCA [cytosol]
_timestamp	2017-06-28 09:52:25
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:4332336] Rothfels, K, 2013-08-16
endCoordinate	672
hasModifiedResidue	[ModifiedResidue:4332335] O-phospho-L-threonine at 497 [ModifiedResidue:4332338] O-phospho-L-threonine at 638 [ModifiedResidue:4332339] O-phospho-L-serine at 657
literatureReference	[LiteratureReference:4332315] Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1) [LiteratureReference:4332313] Protein kinase C is regulated in vivo by three functionally distinct phosphorylations
modified	[InstanceEdit:9010735] Orlic-Milacic, Marija, 2017-06-28
name	p-T497,T638,S657-PRKCA Protein kinase C, alpha type PKC-alpha PKC-A
referenceEntity	[ReferenceGeneProduct:58197] UniProt:P17252 PRKCA [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5647526] R-HSA-4332337.2
startCoordinate	2
(activeUnit)	[CatalystActivity:9010774] calcium,diacylglycerol-dependent serine/threonine kinase activity of ROBO3.1:AKAP5:p-T497,T638,S657-PRKCA [plasma membrane]
(hasComponent)	[Complex:9010732] ROBO2:AKAP5:p-T497,T638,S657-PRKCA [plasma membrane] [Homo sapiens] [Complex:9010754] ROBO3.1:AKAP5:p-T497,T638,S657-PRKCA [plasma membrane] [Homo sapiens] [Complex:9010778] p-S1330-ROBO3.1:AKAP5:p-T497,T638,S657-PRKCA [plasma membrane] [Homo sapiens]
(hasMember)	[DefinedSet:5218758] p-PKC [cytosol] [Homo sapiens] [DefinedSet:9717604] p-2T,S-PRKCA, p-2T,S-PRKCB [cytosol] [Homo sapiens]
(input)	[Reaction:4332390] Translocation and activation of PKC alpha in response to WNT signaling [Homo sapiens] [Reaction:9010643] AKAP5 recruits PKC to ROBO2 [Homo sapiens] [Reaction:9010646] AKAP5 recruits PKC to ROBO3.1 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9897649] Update Tracker - [EntityWithAccessionedSequence:4332337] p-T497,T638,S657-PRKCA [cytosol] - v62:[modifyName]
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No pathways have been reviewed or authored by p-T497,T638,S657-PRKCA [cytosol] (4332337)