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Details on Person BP230 is recruited to the hemidesmosome

Class:Id	Reaction:432956
_displayName	BP230 is recruited to the hemidesmosome
_doRelease	TRUE
_timestamp	2018-04-16 17:54:27
authored	[InstanceEdit:446005] Matthews, L, 2009-11-04
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:432951] Matthews, L, 2009-08-18
edited	[InstanceEdit:446005] Matthews, L, 2009-11-04
input	[Complex:445997] Integrin alpha 6:beta 4:Plectin:BP180:Laminin-322 complex [plasma membrane] [Homo sapiens] [CandidateSet:447012] BP230 [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:446011] The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome
modified	[InstanceEdit:446000] Matthews, L, 2009-11-09 [InstanceEdit:446613] Matthews, L, 2009-11-13 [InstanceEdit:446740] Matthews, L, 2009-11-17 [InstanceEdit:447006] Matthews, L, 2009-11-19 [InstanceEdit:847712] Garapati, P V, 2010-05-31 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:1080825] Garapati, P V, 2010-11-28 [InstanceEdit:9605710] Orlic-Milacic, Marija, 2018-04-16 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	BP230 is recruited to the hemidesmosome
output	[Complex:446010] BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:446089] BP180 interacts extracellularly with Laminin 332 [Homo sapiens] [Reaction:432952] BP180 interacts intracellularly with plectin and integrin beta4 [Homo sapiens]
releaseDate	2009-12-15
reviewed	[InstanceEdit:447005] Sonnenberg, A, 2009-11-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105726] R-HSA-432956.3
summation	[Summation:446009] Following the association of BP180 with the forming hemidesm...
(hasEvent)	[Pathway:446107] Type I hemidesmosome assembly [Homo sapiens]
(precedingEvent)	[Reaction:446083] CD151 interacts with BP180 and the integrin alpha 6 subunit [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9790064] Update Tracker - [Reaction:432956] BP230 is recruited to the hemidesmosome - v35:[addInput] [_UpdateTracker:9790674] Update Tracker - [Reaction:432956] BP230 is recruited to the hemidesmosome - v33:[removeInput]
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No pathways have been reviewed or authored by BP230 is recruited to the hemidesmosome (432956)