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Details on Person Cytosolic JET binds to CRY, facilitating its ubiquitination

Class:Id	BlackBoxEvent:432593
_displayName	Cytosolic JET binds to CRY, facilitating its ubiquitination
_doRelease	TRUE
_timestamp	2020-02-27 14:22:41
authored	[InstanceEdit:432420] Williams, MG, 2009-08-13
catalystActivity	[CatalystActivity:9677108] ubiquitin-like ligase-substrate adaptor activity of JET [cytosol]
catalystActivityReference	[CatalystActivityReference:9677103] protein binding, bridging involved in substrate recognition for ubiquitination activity of JET [cytosol] Roles of F-box proteins in cancer
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:432644] Williams, MG, 2009-08-14
edited	[InstanceEdit:5490376] Williams, MG, 2014-05-20
figure	[Figure:881938] /figures/DrosCircClockC28.jpg
input	[EntityWithAccessionedSequence:432574] CRY [cytosol] [Drosophila melanogaster] [EntityWithAccessionedSequence:432571] JET [cytosol] [Drosophila melanogaster] [DefinedSet:206204] UBI-P63E [cytosol] [Drosophila melanogaster]
literatureReference	[LiteratureReference:432404] Light-dependent interactions between the Drosophila circadian clock factors cryptochrome, jetlag, and timeless
modified	[InstanceEdit:538918] Williams, MG, 2010-03-08 [InstanceEdit:882015] Williams, MG, 2010-06-28 [InstanceEdit:909539] Williams, MG, 2010-07-07 [InstanceEdit:912304] Williams, MG, 2010-07-08 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9024533] Matthews, Lisa, 2017-10-05 [InstanceEdit:9038602] D'Eustachio, Peter, 2018-03-09 [InstanceEdit:9677062] D'Eustachio, Peter, 2020-02-26 [InstanceEdit:9677109] D'Eustachio, Peter, 2020-02-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Cytosolic JET binds to CRY, facilitating its ubiquitination
output	[Complex:432576] UBI-P63E:CRY:JET [cytosol] [Drosophila melanogaster]
precedingEvent	[BlackBoxEvent:432507] Cytosolic TIM is degraded by the 26S proteasome [Drosophila melanogaster] [BlackBoxEvent:432401] JET binds cytosolic TIM, facilitating its ubiquitination [Drosophila melanogaster] [BlackBoxEvent:432401] JET binds cytosolic TIM, facilitating its ubiquitination [Drosophila melanogaster] [Reaction:432426] CRY is activated by light and binds to cytosolic TIM [Drosophila melanogaster] [BlackBoxEvent:432428] Cytosolic CRY is degraded by the 26S proteasome [Drosophila melanogaster] [BlackBoxEvent:432507] Cytosolic TIM is degraded by the 26S proteasome [Drosophila melanogaster] [BlackBoxEvent:432428] Cytosolic CRY is degraded by the 26S proteasome [Drosophila melanogaster] [BlackBoxEvent:432593] Cytosolic JET binds to CRY, facilitating its ubiquitination [Drosophila melanogaster]
releaseDate	2017-09-12
reviewed	[InstanceEdit:909536] Edery, I, 2010-07-06
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:9677063] D'Eustachio, Peter, 2020-02-26
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8884722] R-DME-432593.5
summation	[Summation:432461] After Timeless (TIM) levels drop when it is degraded by the ...
(hasEvent)	[Pathway:538864] Degradation of CRY [Drosophila melanogaster]
(precedingEvent)	[BlackBoxEvent:432428] Cytosolic CRY is degraded by the 26S proteasome [Drosophila melanogaster]
(updatedInstance)	[_UpdateTracker:9777125] Update Tracker - [BlackBoxEvent:432593] Cytosolic JET binds to CRY, facilitating its ubiquitination - v72:[add_removeCatalystActivity, modifyText]
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