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Details on Person CRY is activated by light and binds to cytosolic TIM

Class:Id	Reaction:432426
_displayName	CRY is activated by light and binds to cytosolic TIM
_doRelease	TRUE
_timestamp	2018-03-09 00:12:17
authored	[InstanceEdit:432420] Williams, MG, 2009-08-13
catalystActivity	[CatalystActivity:432519] blue light photoreceptor activity of Photon [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:432644] Williams, MG, 2009-08-14
edited	[InstanceEdit:5490376] Williams, MG, 2014-05-20
figure	[Figure:881910] /figures/DrosCircClockC22.jpg
input	[EntityWithAccessionedSequence:432355] TIM [cytosol] [Drosophila melanogaster] [EntityWithAccessionedSequence:432574] CRY [cytosol] [Drosophila melanogaster]
literatureReference	[LiteratureReference:432493] Roles of the two Drosophila CRYPTOCHROME structural domains in circadian photoreception [LiteratureReference:432583] A constitutively active cryptochrome in Drosophila melanogaster [LiteratureReference:432404] Light-dependent interactions between the Drosophila circadian clock factors cryptochrome, jetlag, and timeless [LiteratureReference:538887] Photic signaling by cryptochrome in the Drosophila circadian system [LiteratureReference:538910] Light-dependent sequestration of TIMELESS by CRYPTOCHROME
modified	[InstanceEdit:538918] Williams, MG, 2010-03-08 [InstanceEdit:882015] Williams, MG, 2010-06-28 [InstanceEdit:909539] Williams, MG, 2010-07-07 [InstanceEdit:912304] Williams, MG, 2010-07-08 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9024533] Matthews, Lisa, 2017-10-05 [InstanceEdit:9038602] D'Eustachio, Peter, 2018-03-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CRY is activated by light and binds to cytosolic TIM
output	[Complex:881918] TIM:CRY [cytosol] [Drosophila melanogaster]
precedingEvent	[BlackBoxEvent:432401] JET binds cytosolic TIM, facilitating its ubiquitination [Drosophila melanogaster] [Reaction:432426] CRY is activated by light and binds to cytosolic TIM [Drosophila melanogaster] [BlackBoxEvent:432428] Cytosolic CRY is degraded by the 26S proteasome [Drosophila melanogaster] [BlackBoxEvent:432507] Cytosolic TIM is degraded by the 26S proteasome [Drosophila melanogaster]
releaseDate	2017-09-12
reviewed	[InstanceEdit:909536] Edery, I, 2010-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8924513] R-DME-432426.4
summation	[Summation:432534] At dawn, a light-induced conformational change in the blue-l...
(hasEvent)	[Pathway:432395] Degradation of TIM [Drosophila melanogaster]
(precedingEvent)	[BlackBoxEvent:432401] JET binds cytosolic TIM, facilitating its ubiquitination [Drosophila melanogaster]
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No pathways have been reviewed or authored by CRY is activated by light and binds to cytosolic TIM (432426)