Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Cytosolic PER is degraded by the 26S proteasome

Class:Id	BlackBoxEvent:432361
_displayName	Cytosolic PER is degraded by the 26S proteasome
_doRelease	TRUE
_timestamp	2018-03-09 00:12:32
authored	[InstanceEdit:432420] Williams, MG, 2009-08-13
catalystActivity	[CatalystActivity:208900] endopeptidase activity of 26S proteasome [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:432644] Williams, MG, 2009-08-14
edited	[InstanceEdit:5490376] Williams, MG, 2014-05-20
figure	[Figure:881996] /figures/DrosCircClockC19.jpg
input	[Complex:881958] SLMB:UBI-P63E:Phospho (multi-site 1) PER:DCO [cytosol] [Drosophila melanogaster]
literatureReference	[LiteratureReference:432526] Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime [LiteratureReference:432446] The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock
modified	[InstanceEdit:538918] Williams, MG, 2010-03-08 [InstanceEdit:882015] Williams, MG, 2010-06-28 [InstanceEdit:909539] Williams, MG, 2010-07-07 [InstanceEdit:912304] Williams, MG, 2010-07-08 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9024533] Matthews, Lisa, 2017-10-05 [InstanceEdit:9038602] D'Eustachio, Peter, 2018-03-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Cytosolic PER is degraded by the 26S proteasome
output	[EntityWithAccessionedSequence:206299] SLMB [cytosol] [Drosophila melanogaster] [EntityWithAccessionedSequence:205729] DCO [cytosol] [Drosophila melanogaster] [DefinedSet:206204] UBI-P63E [cytosol] [Drosophila melanogaster]
precedingEvent	[BlackBoxEvent:432411] SLMB binds phosphorylated cytosolic PER, facilitating its ubiquitination [Drosophila melanogaster] [Reaction:432559] PER is phosphorylated by DCO [Drosophila melanogaster] [BlackBoxEvent:432361] Cytosolic PER is degraded by the 26S proteasome [Drosophila melanogaster]
releaseDate	2017-09-12
reviewed	[InstanceEdit:909536] Edery, I, 2010-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8928591] R-DME-432361.4
summation	[Summation:432624] Ubiquitinated phosphorylated Period (PER) is degraded by the...
(hasEvent)	[Pathway:432524] Degradation of PER [Drosophila melanogaster]
(precedingEvent)	[BlackBoxEvent:432411] SLMB binds phosphorylated cytosolic PER, facilitating its ubiquitination [Drosophila melanogaster] [Reaction:432516] CLK and CYC bind to form a heterodimer [Drosophila melanogaster]
[Change default viewing format]

No pathways have been reviewed or authored by Cytosolic PER is degraded by the 26S proteasome (432361)