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Details on Person Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane

Class:Id	BlackBoxEvent:432237
_displayName	Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane
_doRelease	TRUE
_timestamp	2014-02-03 19:36:38
authored	[InstanceEdit:432201] May, B, 2009-08-11
catalystActivity	[CatalystActivity:2028706] microfilament motor activity of MYO5B:RABFIP2:RAB11A [cytoplasmic vesicle membrane]
compartment	[Compartment:876] plasma membrane [Compartment:13946] transport vesicle membrane
created	[InstanceEdit:432236] May, B, 2009-08-12
edited	[InstanceEdit:432201] May, B, 2009-08-11
input	[Complex:432217] p-S256-AQP2 tetramer [transport vesicle membrane] [Homo sapiens]
literatureReference	[LiteratureReference:432230] Lack of arginine vasopressin-induced phosphorylation of aquaporin-2 mutant AQP2-R254L explains dominant nephrogenic diabetes insipidus [LiteratureReference:432240] Protein kinase A phosphorylation is involved in regulated exocytosis of aquaporin-2 in transfected LLC-PK1 cells [LiteratureReference:432234] The subcellular localization of an aquaporin-2 tetramer depends on the stoichiometry of phosphorylated and nonphosphorylated monomers [LiteratureReference:432214] The role of putative phosphorylation sites in the targeting and shuttling of the aquaporin-2 water channel [LiteratureReference:2028700] A Role of myosin Vb and Rab11-FIP2 in the aquaporin-2 shuttle [LiteratureReference:2028703] Effect of a dynein inhibitor on vasopressin action in toad urinary bladder
modified	[InstanceEdit:432255] May, B, 2009-08-12 [InstanceEdit:503946] May, B, 2010-02-05 [InstanceEdit:771692] May, B, 2010-05-21 [InstanceEdit:847706] May, B, 2010-05-30 [InstanceEdit:879864] May, B, 2010-06-24 [InstanceEdit:913480] May, B, 2010-07-15 [InstanceEdit:918084] May, B, 2010-07-31 [InstanceEdit:927718] May, B, 2010-08-06 [InstanceEdit:2028708] May, B, 2011-12-31 [InstanceEdit:5251387] May, B, 2014-02-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane
output	[Complex:432226] p-S256-AQP2 tetramer [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:432232] Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) [Homo sapiens] [Reaction:111925] cAMP induces dissociation of inactive PKA tetramers [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:879857] Beitz, E, 2010-06-24 [InstanceEdit:913479] Calamita, G, 2010-07-15 [InstanceEdit:918100] Mathai, JC, MacIver, B, 2010-07-31
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105121] R-HSA-432237.2
summation	[Summation:432225] Intracellular vesicles bearing phosphorylated Aquaporin-2 te...
(hasEvent)	[Pathway:432040] Vasopressin regulates renal water homeostasis via Aquaporins [Homo sapiens]
(precedingEvent)	[Reaction:432065] p-S256-Aquaporin-2 passively transports water into cell [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9788803] Update Tracker - [BlackBoxEvent:432237] Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane - v40:[addCatalystActivity, addLiteratureReference, modifyText]
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