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Details on Person Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor
Class:Id Reaction:432172
_displayName Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor
_doRelease TRUE
_timestamp 2019-12-17 16:40:39
authored [InstanceEdit:445353] Mahajan, SS, 2009-10-29
compartment [Compartment:984] extracellular region [Compartment:876] plasma membrane [Compartment:70101] cytosol
created [InstanceEdit:432173] Mahajan, SS, 2009-08-12
edited [InstanceEdit:422554] Gillespie, ME, 2009-06-02 00:56:21 [InstanceEdit:9615242] Orlic-Milacic, Marija, 2018-07-31 [InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
inferredFrom
input [SimpleEntity:210382] L-Glu [extracellular region] [Complex:9614184] GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] [Homo sapiens] [SimpleEntity:210382] L-Glu [extracellular region] [DefinedSet:9627662] Gly,D-Ser [extracellular region] [DefinedSet:9627662] Gly,D-Ser [extracellular region]
modified [InstanceEdit:432785] Mahajan, SS, 2009-08-17 [InstanceEdit:438033] Mahajan, SS, 2009-09-23 [InstanceEdit:442708] Mahajan, SS, 2009-09-29 [InstanceEdit:444282] Mahajan, SS, 2009-10-23 [InstanceEdit:444800] Mahajan, SS, 2009-10-26 [InstanceEdit:445390] Mahajan, SS, 2009-10-30 [InstanceEdit:446817] Mahajan, SS, 2009-11-17 [InstanceEdit:447281] Mahajan, SS, 2009-11-21 [InstanceEdit:8849195] Garapati, Phani Vijay, 2015-12-14 [InstanceEdit:9614331] Orlic-Milacic, Marija, 2018-07-24 [InstanceEdit:9614336] Orlic-Milacic, Marija, 2018-07-24 [InstanceEdit:9614360] Orlic-Milacic, Marija, 2018-07-24 [InstanceEdit:9615245] Orlic-Milacic, Marija, 2018-07-31 [InstanceEdit:9627665] Orlic-Milacic, Marija, 2018-11-02 [InstanceEdit:9628237] Orlic-Milacic, Marija, 2018-11-07 [InstanceEdit:9628240] Orlic-Milacic, Marija, 2018-11-07 [InstanceEdit:9628439] Orlic-Milacic, Marija, 2018-11-08 [InstanceEdit:9670982] Jassal, Bijay, 2019-12-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor
output [Complex:9614256] Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate 2009-12-15
reviewed [InstanceEdit:446792] Tukey, D, 2009-11-17 [InstanceEdit:9627687] Yi, Feng, 2018-11-02 [InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
reviewStatus [ReviewStatus:9821382] five stars
revised [InstanceEdit:9624342] Orlic-Milacic, Marija, 2018-10-10
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1104642] R-HSA-432172.6
summation [Summation:444283] NMDA receptors require binding of two ligands: agonist, glut...
(hasEvent) [Pathway:438066] Unblocking of NMDA receptors, glutamate binding and activation [Homo sapiens]
(precedingEvent) [Reaction:432162] Unblocking of GRIN1:GRIN2 NMDA receptors [Homo sapiens] [Reaction:432164] Ca2+ influx into the post-synaptic cell [Homo sapiens]
(updatedInstance) [_UpdateTracker:9778778] Update Tracker - [Reaction:432172] Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor - v67:[add_removeInput, modifyText] [_UpdateTracker:9779087] Update Tracker - [Reaction:432172] Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor - v66:[add_removeInput, add_removeOutput, modifyText, removeLiteratureReference]
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