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Details on Person FGR binds and phosphorylates LRP8

Class:Id	Reaction:432129
_displayName	FGR binds and phosphorylates LRP8
_doRelease	TRUE
_timestamp	2016-11-08 14:28:11
authored	[InstanceEdit:435013] Akkerman, JW, 2009-09-04
catalystActivity	[CatalystActivity:432134] protein tyrosine kinase activity of LDL:LRP8:FGR [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:432130] Jupe, S, 2009-08-11
edited	[InstanceEdit:870306] Jupe, S, 2010-06-07
input	[Complex:8948036] LDL:LRP8:FGR [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:432126] Binding of low density lipoprotein to platelet apolipoprotein E receptor 2' results in phosphorylation of p38MAPK
modified	[InstanceEdit:432314] Jupe, S, 2009-08-13 [InstanceEdit:435228] Jupe, S, 2009-09-08 [InstanceEdit:870420] Jupe, S, 2010-06-08 [InstanceEdit:938686] Jupe, S, 2010-08-31 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:2424261] Jassal, B, 2012-07-23 [InstanceEdit:8948035] Jupe, Steve, 2016-11-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FGR binds and phosphorylates LRP8
output	[Complex:432132] LDL:p-LRP8:FGR [plasma membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:8948034] FGR binds LDL:LRP8 [Homo sapiens] [Reaction:432121] LDL binds to LRP8 [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104960] R-HSA-432129.3
summation	[Summation:432131] Tyrosine phosphorylation of LDL:LRP8 is mediated by the Src-...
(hasEvent)	[Pathway:432142] Platelet sensitization by LDL [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:432148] Fgr may phosphorylate p38 MAPK [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9782402] Update Tracker - [Reaction:432129] FGR binds and phosphorylates LRP8 - v59:[add_removeInput] [_UpdateTracker:9788379] Update Tracker - [Reaction:432129] FGR binds and phosphorylates LRP8 - v42:[modifyText]
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No pathways have been reviewed or authored by FGR binds and phosphorylates LRP8 (432129)