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Details on Person Aquaporin-1 passively transports water into cell
Class:Id Reaction:432010
_displayName Aquaporin-1 passively transports water into cell
_doRelease TRUE
_timestamp 2014-02-03 19:35:24
authored [InstanceEdit:432015] May, B, 2009-08-06
catalystActivity [CatalystActivity:432032] water channel activity of AQP1 tetramer [plasma membrane]
catalystActivityReference [CatalystActivityReference:9643556] water channel activity of AQP1 tetramer [plasma membrane] Aquaporin-1, nothing but a water channel
compartment [Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created [InstanceEdit:432025] May, B, 2009-08-08
edited [InstanceEdit:432015] May, B, 2009-08-06
input [SimpleEntity:109276] H2O [extracellular region]
literatureReference [LiteratureReference:431931] Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules [LiteratureReference:431795] CHIP28 water channels are localized in constitutively water-permeable segments of the nephron [LiteratureReference:431685] Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein [LiteratureReference:431981] Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein [LiteratureReference:431788] Bidirectional water fluxes and specificity for small hydrophilic molecules in aquaporins 0-5 [LiteratureReference:431881] Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas [LiteratureReference:503955] Mechanism of selectivity in aquaporins and aquaglyceroporins [LiteratureReference:503995] Aquaporin-1, nothing but a water channel [LiteratureReference:503972] Expression of the AQP-1 water channel in normal human tissues: a semiquantitative study using tissue microarray technology [LiteratureReference:503973] Aquaporin expression in normal human kidney and in renal disease [LiteratureReference:504004] Structural determinants of water permeation through aquaporin-1 [LiteratureReference:879852] Concerted action of two cation filters in the aquaporin water channel [LiteratureReference:879877] Point mutations in the aromatic/arginine region in aquaporin 1 allow passage of urea, glycerol, ammonia, and protons
modified [InstanceEdit:503946] May, B, 2010-02-05 [InstanceEdit:771692] May, B, 2010-05-21 [InstanceEdit:847706] May, B, 2010-05-30 [InstanceEdit:879864] May, B, 2010-06-24 [InstanceEdit:913480] May, B, 2010-07-15 [InstanceEdit:918084] May, B, 2010-07-31 [InstanceEdit:927718] May, B, 2010-08-06 [InstanceEdit:5251387] May, B, 2014-02-03 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Aquaporin-1 passively transports water into cell
output [SimpleEntity:29356] H2O [cytosol]
releaseDate 2010-09-21
reverseReaction
reviewed [InstanceEdit:879857] Beitz, E, 2010-06-24 [InstanceEdit:913479] Calamita, G, 2010-07-15 [InstanceEdit:918100] Mathai, JC, MacIver, B, 2010-07-31
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1104871] R-HSA-432010.3
summation [Summation:431698] Aquaporin-1 (AQP1) passively transports water across the pla...
(hasEvent) [Pathway:432040] Vasopressin regulates renal water homeostasis via Aquaporins [Homo sapiens]
(precedingEvent) [Reaction:432054] Aquaporin-1 passively transports water out of cell [Homo sapiens]
(reverseReaction) [Reaction:432054] Aquaporin-1 passively transports water out of cell [Homo sapiens]
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