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Details on Person FASL:FAS Receptor Trimer:FADD [plasma membrane]

Class:IdComplex:43124
_displayNameFASL:FAS Receptor Trimer:FADD [plasma membrane]
_timestamp2023-06-05 16:19:15
compartment[Compartment:876] plasma membrane
hasComponent
literatureReference[LiteratureReference:3465522] Ebselen sensitizes glioblastoma cells to Tumor Necrosis Factor (TNFalpha)-induced apoptosis through two distinct pathways involving NF-kappaB downregulation and Fas-mediated formation of death inducing signaling complex
[LiteratureReference:3465531] Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis
modified[InstanceEdit:109917] Joshi-Tope, G, 2004-01-22 15:11:19
[InstanceEdit:113466] Schmidt, EE, 2004-05-17 04:24:53
[InstanceEdit:3371406] Shamovsky, V, 2013-05-13
[InstanceEdit:3465516] Shamovsky, V, 2013-05-17
[InstanceEdit:3465534] Shamovsky, V, 2013-05-17
[InstanceEdit:5263596] D'Eustachio, Peter, 2014-02-11
[InstanceEdit:5340167] Shamovsky, V, 2014-03-10
[InstanceEdit:9836868] D'Eustachio, Peter, 2023-06-05
nameFASL:FAS Receptor Trimer:FADD
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:366491] R-HSA-43124.2
(hasComponent)[Complex:75114] FASL:FAS trimer:FADD:CASP8(1-479) [plasma membrane] [Homo sapiens]
[Complex:141315] FASL:FAS Receptor Trimer:FADD:pro-Caspase-10 [plasma membrane] [Homo sapiens]
[Complex:2671811] FASL:FAS receptor trimer:FADD:procaspase-8-dimer [plasma membrane] [Homo sapiens]
[Complex:3465499] FASL:FAS Receptor Trimer:FADD:pro-Caspase-8:FLIP(L) [plasma membrane] [Homo sapiens]
(hasMember)[DefinedSet:2671814] DISC [plasma membrane] [Homo sapiens]
(input)[Reaction:83586] FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 [Homo sapiens]
[Reaction:141310] FASL:FAS Receptor Trimer:FADD complex binds procaspase-10 [Homo sapiens]
[Reaction:5334739] HPV Suppressed FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 [Homo sapiens]
(output)[Reaction:83650] FasL:Fas binds FADD [Homo sapiens]
(updatedInstance)[_UpdateTracker:9883151] Update Tracker - [Complex:43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] - v45:[addLiteratureReference, modifyName]
[_UpdateTracker:9888926] Update Tracker - [Complex:43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] - v48:[addCompartment, updateContainedComponent]
[_UpdateTracker:9889525] Update Tracker - [Complex:43124] FASL:FAS Receptor Trimer:FADD [plasma membrane] - v49:[removeCompartment, updateContainedComponent]
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No pathways have been reviewed or authored by FASL:FAS Receptor Trimer:FADD [plasma membrane] (43124)
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