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Details on Person GP1b-IX-V binds 14-3-3-zeta

Class:Id	Reaction:430076
_displayName	GP1b-IX-V binds 14-3-3-zeta
_doRelease	TRUE
_timestamp	2016-05-23 09:16:01
authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:430080] Jupe, S, 2009-07-30
edited	[InstanceEdit:870306] Jupe, S, 2010-06-07
input	[Complex:435464] GpIb-IX-V:Collagen type I fibril:vWF [plasma membrane] [Homo sapiens] [Complex:206751] YWHAZ dimer [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:430077] Association of a phospholipase A2 (14-3-3 protein) with the platelet glycoprotein Ib-IX complex [LiteratureReference:430071] Binding of purified 14-3-3 zeta signaling protein to discrete amino acid sequences within the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex [LiteratureReference:430068] Cytoplasmic domains of GpIbalpha and GpIbbeta regulate 14-3-3zeta binding to GpIb/IX/V [LiteratureReference:430067] Identification of a binding sequence for the 14-3-3 protein within the cytoplasmic domain of the adhesion receptor, platelet glycoprotein Ib alpha
modified	[InstanceEdit:435397] Jupe, S, 2009-09-09 [InstanceEdit:443417] Jupe, S, 2009-10-06 [InstanceEdit:870420] Jupe, S, 2010-06-08 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8874334] Jupe, Steve, 2016-05-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	GP1b-IX-V binds 14-3-3-zeta
output	[Complex:429544] GPIb-IX-V:Collagen type I fibril:vWF:14-3-3-zeta [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:114670] GPIb-IX-V binds to vWF:Collagen complex [Homo sapiens] [Reaction:114671] vWF binds to collagen [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104384] R-HSA-430076.3
summation	[Summation:430079] The Gp1b-IX-V complex binds to 14-3-3-zeta, a scaffolding pr...
(hasEvent)	[Pathway:430116] GP1b-IX-V activation signalling [Homo sapiens]
(precedingEvent)	[Reaction:430073] GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress [Homo sapiens] [Reaction:443402] GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K [Homo sapiens] [Reaction:443831] 14-3-3-zeta binds Raf1 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9782959] Update Tracker - [Reaction:430076] GP1b-IX-V binds 14-3-3-zeta - v58:[add_removeInput]
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