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Details on Person GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress

Class:Id	Reaction:430073
_displayName	GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress
_doRelease	TRUE
_timestamp	2016-05-23 09:16:20
authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:430074] Jupe, S, 2009-07-30
edited	[InstanceEdit:870306] Jupe, S, 2010-06-07
input	[Complex:429544] GPIb-IX-V:Collagen type I fibril:vWF:14-3-3-zeta [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:430093] The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress
modified	[InstanceEdit:430089] Jupe, S, 2009-07-30 [InstanceEdit:434803] Jupe, S, 2009-09-03 [InstanceEdit:443417] Jupe, S, 2009-10-06 [InstanceEdit:870420] Jupe, S, 2010-06-08 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8874334] Jupe, Steve, 2016-05-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress
output	[Complex:206751] YWHAZ dimer [cytosol] [Homo sapiens] [Complex:435464] GpIb-IX-V:Collagen type I fibril:vWF [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:430076] GP1b-IX-V binds 14-3-3-zeta [Homo sapiens] [Reaction:114670] GPIb-IX-V binds to vWF:Collagen complex [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104257] R-HSA-430073.3
summation	[Summation:430070] High shear stress, or immobilization of VWF under high shear...
(hasEvent)	[Pathway:430116] GP1b-IX-V activation signalling [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9782734] Update Tracker - [Reaction:430073] GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress - v58:[add_removeOutput]
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