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Details on Person Passive I- efflux mediated by SLC5A8

Class:Id	Reaction:429767
_displayName	Passive I- efflux mediated by SLC5A8
_doRelease	TRUE
_timestamp	2025-06-26 07:54:54
authored	[InstanceEdit:429759] Jassal, Bijay, 2009-07-21
catalystActivity	[CatalystActivity:429741] iodide channel activity of SLC5A8 [plasma membrane]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:429759] Jassal, Bijay, 2009-07-21
crossReference	[DatabaseIdentifier:9958938] RHEA:66325
edited	[InstanceEdit:429759] Jassal, Bijay, 2009-07-21
input	[SimpleEntity:209785] I- [cytosol]
literatureReference	[LiteratureReference:429747] Identification and characterization of a putative human iodide transporter located at the apical membrane of thyrocytes
modified	[InstanceEdit:433652] Jassal, Bijay, 2009-08-24 [InstanceEdit:1614621] Jassal, Bijay, 2011-09-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9909148] D'Eustachio, Peter, 2024-04-29 [InstanceEdit:9958940] Stephan, Ralf, 2025-06-26
name	Passive I- efflux mediated by SLC5A8
output	[SimpleEntity:209818] I- [extracellular region]
precedingEvent	[Reaction:429591] SLC5A5 cotransports Na+ with I- from extracellular region to cytosol [Homo sapiens] [Reaction:429767] Passive I- efflux mediated by SLC5A8 [Homo sapiens]
releaseDate	2009-09-30
reviewed	[InstanceEdit:433651] He, L, 2009-08-24
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104606] R-HSA-429767.4
summation	[Summation:429745] SLC5A8 encodes the apical iodide transporter, AIT (also know...
(hasEvent)	[Pathway:9958790] SLC-mediated transport of inorganic anions [Homo sapiens]
(precedingEvent)	[Reaction:429591] SLC5A5 cotransports Na+ with I- from extracellular region to cytosol [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9910996] Update Tracker - [Reaction:429767] Passive I- efflux mediated by SLC5A8 - v89:[modifyText]
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No pathways have been reviewed or authored by Passive I- efflux mediated by SLC5A8 (429767)