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Details on Person Multiphospho-CERT (ceramide transfer protein) associates wit...
| Class:Id | Summation:429731 |
|---|---|
| _displayName | Multiphospho-CERT (ceramide transfer protein) associates wit... |
| _timestamp | 2025-06-16 19:32:43 |
| created | [InstanceEdit:429733] D'Eustachio, P, 2009-07-20 |
| modified | [InstanceEdit:429734] D'Eustachio, P, 2009-07-20 [InstanceEdit:9843191] Stephan, Ralf, 2023-09-02 [InstanceEdit:9845645] Stephan, Ralf, 2023-10-07 [InstanceEdit:9956913] D'Eustachio, Peter, 2025-06-16 |
| text | Multiphospho-CERT (ceramide transfer protein) associates with the complex of VAPA/B (VAMP-associated proteins A or B) and PPM1L (protein phosphatase 1-like) in the endoplasmic reticulum membrane (Kawano et al. 2006; Saito et al. 2008; Kumagai & Hanada 2019), enabling PPM1L to catalyze the dephosphorylation of the multiphospho-CERT complex component (Saito et al. 2008; Kumagai & Hanada 2019). This dephosphorylation restores CERT’s ability to bind and transport ceramide. |
| (summation) | [Reaction:429730] PPM1L dephosphorylates multiphospho-CERT1-2 [Homo sapiens] |
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No pathways have been reviewed or authored by Multiphospho-CERT (ceramide transfer protein) associates wit... (429731)
