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Details on Person CSNK1G2 phosphorylates p-CERT1-2
Class:Id Reaction:429714
_displayName CSNK1G2 phosphorylates p-CERT1-2
_doRelease TRUE
_timestamp 2024-03-04 22:22:43
authored [InstanceEdit:433041] D'Eustachio, P, 2009-08-20
catalystActivity [CatalystActivity:429721] protein serine/threonine kinase activity of CSNK1G2 [cytosol]
compartment [Compartment:70101] cytosol
created [InstanceEdit:429702] D'Eustachio, P, 2009-07-18
edited [InstanceEdit:433041] D'Eustachio, P, 2009-08-20
input [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [EntityWithAccessionedSequence:429704] p-S132-CERT1-2 [cytosol] [Homo sapiens]
literatureReference [LiteratureReference:429709] Casein kinase I{gamma}2 down-regulates trafficking of ceramide in the synthesis of sphingomyelin [LiteratureReference:9843187] Structure, functions and regulation of CERT, a lipid-transfer protein for the delivery of ceramide at the ER-Golgi membrane contact sites
modified [InstanceEdit:429723] D'Eustachio, P, 2009-07-18 [InstanceEdit:429733] D'Eustachio, P, 2009-07-20 [InstanceEdit:433040] D'Eustachio, P, 2009-08-20 [InstanceEdit:446904] D'Eustachio, P, 2009-11-18 [InstanceEdit:1660664] Jassal, B, 2011-10-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9841785] Stephan, Ralf, 2023-08-12 [InstanceEdit:9843191] Stephan, Ralf, 2023-09-02 [InstanceEdit:9845639] Stephan, Ralf, 2023-10-07 [InstanceEdit:9851294] Stephan, Ralf, 2023-10-20 [InstanceEdit:9851343] Stephan, Ralf, 2023-10-24 [InstanceEdit:9851352] Stephan, Ralf, 2023-10-24 [InstanceEdit:9853090] Matthews, Lisa, 2023-11-14 [InstanceEdit:9863709] D'Eustachio, Peter, 2024-03-04
name CSNK1G2 phosphorylates p-CERT1-2 monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP
output [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [EntityWithAccessionedSequence:429695] p-S,S132,T-CERT1-2 [cytosol] [Homo sapiens] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:70106] H+ [cytosol]
precedingEvent
previousReviewStatus [ReviewStatus:9821384] two stars
releaseDate 2009-09-30
reviewed [InstanceEdit:446905] Hannun, YA, Luberto, C, 2009-11-18 [InstanceEdit:433039] Jassal, B, 2009-08-20 [InstanceEdit:9851344] D'Eustachio, Peter, 2023-10-24 [InstanceEdit:9863708] D'Eustachio, Peter, 2024-03-04
reviewStatus [ReviewStatus:9821382] five stars
revised [InstanceEdit:9851456] D'Eustachio, Peter, 2023-10-26
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1105168] R-HSA-429714.5
structureModified [InstanceEdit:9845639] Stephan, Ralf, 2023-10-07 [InstanceEdit:9851352] Stephan, Ralf, 2023-10-24
summation [Summation:429701] Cytosolic CSNK1G2 (casein kinase 1, gamma 2) catalyzes the p...
(hasEvent) [Pathway:1660661] Sphingolipid de novo biosynthesis [Homo sapiens]
(updatedInstance) [_UpdateTracker:9782405] Update Tracker - [Reaction:429714] monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP - v59:[modifyText] [_UpdateTracker:9783343] Update Tracker - [Reaction:429714] monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP - v57:[modifyText] [_UpdateTracker:9784768] Update Tracker - [Reaction:429714] monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP - v53:[modifyText] [_UpdateTracker:9789770] Update Tracker - [Reaction:429714] monophospho-CERT + 2 ATP => multiphospho-CERT + 2 ADP - v37:[modifyText] [_UpdateTracker:9853248] Update Tracker - [Reaction:429714] CSNK1G2 phosphorylates p-CERT1-2 - v87:[addLiteratureReference, addOutput, modifyText]
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