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Details on Person Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6

Class:Id	Reaction:429571
_displayName	Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6
_doRelease	TRUE
_timestamp	2025-06-13 15:24:17
authored	[InstanceEdit:429634] Jassal, Bijay, 2009-07-17
catalystActivity	[CatalystActivity:429661] polyol transmembrane transporter activity of SLC5A11 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:429634] Jassal, Bijay, 2009-07-17
crossReference	[DatabaseIdentifier:9956753] RHEA:73316 [DatabaseIdentifier:9956752] RHEA:72988
edited	[InstanceEdit:429634] Jassal, Bijay, 2009-07-17
input	[DefinedSet:429652] Inositols transported by SMIT2 [extracellular region] [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:74113] Na+ [extracellular region]
literatureReference	[LiteratureReference:429625] New human sodium/glucose cotransporter gene (KST1): identification, characterization, and mutation analysis in ICCA (infantile convulsions and choreoathetosis) and BFIC (benign familial infantile convulsions) families [LiteratureReference:429597] A stereospecific myo-inositol/D-chiro-inositol transporter in HepG2 liver cells. Identification with D-chiro-[3-3H]inositol [LiteratureReference:429636] Human sodium/inositol cotransporter 2 (SMIT2) transports inositols but not glucose in L6 cells
modified	[InstanceEdit:433652] Jassal, Bijay, 2009-08-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9956750] Stephan, Ralf, 2025-06-13
name	Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6
output	[DefinedSet:429648] Inositols transported by SMIT2 [cytosol] [SimpleEntity:83910] Na+ [cytosol] [SimpleEntity:83910] Na+ [cytosol]
releaseDate	2009-09-30
reviewed	[InstanceEdit:433651] He, L, 2009-08-24
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105160] R-HSA-429571.3
summation	[Summation:429609] The human SLC5A11 gene encodes a high affinity myo-inositol ...
(hasEvent)	[Pathway:429593] Inositol transporters [Homo sapiens]
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No pathways have been reviewed or authored by Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (429571)