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Details on Person insulin analogue binding to IR

Class:Id	Reaction:429404
_displayName	insulin analogue binding to IR
_doRelease	FALSE
_timestamp	2016-07-15 23:49:34
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:429396] Shamovsky, V, 2009-07-15
input	[Complex:74675] Insulin receptor [plasma membrane] [Homo sapiens] [DefinedSet:429407] Human Insulin Analogues [extracellular region] [Homo sapiens]
literatureReference	[LiteratureReference:429395] Characteristics of signalling properties mediated by long-acting insulin analogue glargine and detemir in target cells of insulin [LiteratureReference:429353] Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use
modified	[InstanceEdit:429482] Shamovsky, V, 2009-07-15 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	insulin analogue binding to IR
output	[Complex:429403] insulin_analogue: insulin receptor [plasma membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:74734] Re-integration of insulin receptor into plasma membrane [Homo sapiens] [Reaction:74733] Insulin receptor de-phosphorylation [Homo sapiens] [Reaction:429380] Insulin Glargine hexamer dissociates [Homo sapiens] [Reaction:429338] insulin detemir hexamer dissociates [Homo sapiens] [Reaction:429365] insulin detemir multimer:albumin dissociates [Homo sapiens] [Reaction:429481] insulin detemir dimer dissociates [Homo sapiens] [Reaction:429365] insulin detemir multimer:albumin dissociates [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8898735] R-HSA-429404.1
summation	[Summation:429379] The following genetic recombinations of human insulin: insul...
(hasEvent)	[Pathway:429336] Effects of modified insulins [Homo sapiens]
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No pathways have been reviewed or authored by insulin analogue binding to IR (429404)