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Details on Person ABCC4 accumulation of dense granule contents

Class:Id	Reaction:429157
_displayName	ABCC4 accumulation of dense granule contents
_doRelease	TRUE
_timestamp	2021-04-14 09:13:45
authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
catalystActivity	[CatalystActivity:429152] ABC-type transporter activity of ABCC4 [platelet dense granule membrane]
compartment	[Compartment:114584] platelet dense granule membrane [Compartment:70101] cytosol [Compartment:114524] platelet dense granule lumen
created	[InstanceEdit:429162] Jupe, S, 2009-07-14
edited	[InstanceEdit:870306] Jupe, S, 2010-06-07
input	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:29356] H2O [cytosol]
literatureReference	[LiteratureReference:429167] The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage
modified	[InstanceEdit:430358] Jupe, S, 2009-08-07 [InstanceEdit:870420] Jupe, S, 2010-06-08 [InstanceEdit:1472887] Jassal, Bijay, 2011-08-04 [InstanceEdit:8944477] Jupe, Steve, 2016-11-03 [InstanceEdit:9727169] Jassal, Bijay, 2021-04-14 [InstanceEdit:9727174] Jassal, Bijay, 2021-04-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ABCC4 accumulation of dense granule contents
output	[SimpleEntity:114565] ADP [platelet dense granule lumen] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:29372] Pi [cytosol]
releaseDate	2010-09-21
reviewed	[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:9727173] Jassal, Bijay, 2021-04-14
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105177] R-HSA-429157.4
summation	[Summation:429168] ABCC4 (Multidrug resistance protein 4 /MOAT-B) is a member o...
(hasEvent)	[Pathway:114608] Platelet degranulation [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9776104] Update Tracker - [Reaction:429157] ABCC4 accumulation of dense granule contents - v77:[addInput, addOutput, modifyText] [_UpdateTracker:9782575] Update Tracker - [Reaction:429157] ABCC4 accumulation of dense granule contents - v59:[add_removeInput, add_removeOutput]
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No pathways have been reviewed or authored by ABCC4 accumulation of dense granule contents (429157)