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Details on Person SLC2A6,8,10,12 transport Glc from extracellular region to cytosol

Class:Id	Reaction:429094
_displayName	SLC2A6,8,10,12 transport Glc from extracellular region to cytosol
_doRelease	TRUE
_timestamp	2025-08-14 08:00:02
authored	[InstanceEdit:429100] Jassal, Bijay, 2009-07-14
catalystActivity	[CatalystActivity:429072] D-glucose transmembrane transporter activity of SLC2A6,8,10,12 [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:429100] Jassal, Bijay, 2009-07-14
edited	[InstanceEdit:429100] Jassal, Bijay, 2009-07-14
input	[SimpleEntity:70115] Glc [extracellular region]
literatureReference	[LiteratureReference:429063] Activity and genomic organization of human glucose transporter 9 (GLUT9), a novel member of the family of sugar-transport facilitators predominantly expressed in brain and leucocytes [LiteratureReference:429043] GLUT8, a novel member of the sugar transport facilitator family with glucose transport activity [LiteratureReference:429132] Molecular cloning of a novel member of the GLUT family of transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility [LiteratureReference:429099] Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome [LiteratureReference:429134] Identification of a novel glucose transporter-like protein-GLUT-12
modified	[InstanceEdit:429169] Jassal, Bijay, 2009-07-14 [InstanceEdit:429634] Jassal, Bijay, 2009-07-17 [InstanceEdit:433652] Jassal, Bijay, 2009-08-24 [InstanceEdit:5632829] Jassal, Bijay, 2014-10-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9963472] Stephan, Ralf, 2025-08-14
name	SLC2A6,8,10,12 transport Glc from extracellular region to cytosol Glucose transport by class III GLUTs
negativePrecedingEvent	[NegativePrecedingEvent:9963477] Futile Cycle: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region [NegativePrecedingEvent:9963473] Futile Cycle: SLC50A1 transports Glc from cytosol to extracellular region
output	[SimpleEntity:70113] Glc [cytosol]
releaseDate	2009-09-30
reviewed	[InstanceEdit:433651] He, L, 2009-08-24
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105133] R-HSA-429094.3
summation	[Summation:429142] Class III facilitative transporters consist of five members;...
(hasEvent)	[Pathway:189200] Cellular hexose transport [Homo sapiens]
(normalReaction)	[FailedReaction:5632871] Defective SLC2A10 does not transport Glc from extracellular region to cytosol [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9963431] Futile Cycle: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol [NegativePrecedingEvent:9963454] Futile Cycle: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol
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