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Details on Person Acyltransferase which mediates the conversion of lysophospha...

Class:IdSummation:428997
_displayNameAcyltransferase which mediates the conversion of lysophospha...
_timestamp2009-07-14 10:17:51
created[InstanceEdit:428996] Jupe, S, 2009-07-14
textAcyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). Also catalyzes the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity), and has weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.
(summation)[Reaction:429005] Lysophospholipid acyltransferase 5 converts lysophosphatidylcholine to phosphatidylcholine [Homo sapiens]
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