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Details on Person P2Y purinoceptor 1 activates MAP kinase p38 alpha

Class:Id	BlackBoxEvent:428941
_displayName	P2Y purinoceptor 1 activates MAP kinase p38 alpha
_doRelease	TRUE
_timestamp	2012-04-23 13:18:36
authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
catalystActivity	[CatalystActivity:2206199] GTPase activity of G-protein alpha (q/11): GTP [plasma membrane]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:428943] Jupe, S, 2009-07-13
edited	[InstanceEdit:445674] Jupe, S, 2009-11-03
input	[EntityWithAccessionedSequence:428933] MAPK14 [cytosol] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:428944] The P2Y1 receptor mediates ADP-induced p38 kinase-activating factor generation in human platelets
modified	[InstanceEdit:428966] Jupe, S, 2009-07-13 [InstanceEdit:434806] Jupe, S, 2009-09-03 [InstanceEdit:445674] Jupe, S, 2009-11-03 [InstanceEdit:446292] Jupe, S, 2009-11-12 [InstanceEdit:2206198] Jupe, S, 2012-04-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	P2Y purinoceptor 1 activates MAP kinase p38 alpha
output	[EntityWithAccessionedSequence:428935] p-T180,Y182-MAPK14 [cytosol] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:418576] Dissociation of the P2Y purinoceptor 1:Gq complex [Homo sapiens] [Reaction:418579] Gq activation by P2Y purinoceptor 1 [Homo sapiens]
releaseDate	2009-12-15
reviewed	[InstanceEdit:445668] Poole, AW, 2009-11-02 [InstanceEdit:445653] Jones, ML, 2009-11-02 [InstanceEdit:445649] Harper, MT, 2009-11-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105305] R-HSA-428941.2
summation	[Summation:428942] ADP activates human platelets and induces endothelial cell m...
(hasEvent)	[Pathway:418592] ADP signalling through P2Y purinoceptor 1 [Homo sapiens]
(precedingEvent)	[Reaction:428961] Phosphorylation of cPLA2 by MAPK p38 alpha [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9788637] Update Tracker - [BlackBoxEvent:428941] P2Y purinoceptor 1 activates MAP kinase p38 alpha - v41:[addCatalystActivity, modifyText, removeInput]
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No pathways have been reviewed or authored by P2Y purinoceptor 1 activates MAP kinase p38 alpha (428941)