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Details on Person Thromboxane (TXA2) binds to the thromboxane receptor (TP). T...
| Class:Id | Summation:428922 |
|---|---|
| _displayName | Thromboxane (TXA2) binds to the thromboxane receptor (TP). T... |
| _timestamp | 2010-06-02 14:35:07 |
| created | [InstanceEdit:428924] Jupe, S, 2009-07-13 |
| literatureReference | [Book:428928] 9780781749961 Hemostasis and Thrombosis: Basic Principles and Clinical Practice Colman, R [LiteratureReference:870189] Cell signalling through thromboxane A2 receptors |
| modified | [InstanceEdit:434997] Jupe, S, 2009-09-04 [InstanceEdit:870198] Jupe, S, 2010-06-02 |
| text | Thromboxane (TXA2) binds to the thromboxane receptor (TP). There are 2 splice variant forms of TP, differing in their cytoplasmic carboxyl terminal tails. TP beta was first identified in endothelial cells. TP alpha was identified in platelets and placenta. The major signalling route for TP is Gq-mediated stimulation of PLC and consequent increase in cellular calcium. TP also couples to G13, leading to stimulation of Rho and Rac. |
| (summation) | [Pathway:428930] Thromboxane signalling through TP receptor [Homo sapiens] |
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No pathways have been reviewed or authored by Thromboxane (TXA2) binds to the thromboxane receptor (TP). T... (428922)
