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Details on Person SGPP1,2 dephosphorylate sphingoid-1-phosphates

Class:IdReaction:428664
_displayNameSGPP1,2 dephosphorylate sphingoid-1-phosphates
_doReleaseTRUE
_timestamp2024-02-29 18:26:05
authored[InstanceEdit:433041] D'Eustachio, P, 2009-08-20
catalystActivity[CatalystActivity:428700] sphingosine-1-phosphate phosphatase activity of SGPP [endoplasmic reticulum membrane]
compartment[Compartment:70101] cytosol
[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:428672] D'Eustachio, P, 2009-07-06
edited[InstanceEdit:433041] D'Eustachio, P, 2009-08-20
input[SimpleEntity:29356] H2O [cytosol]
[SimpleEntity:5279322] S1P [cytoplasm]
literatureReference[LiteratureReference:428659] Identification and characterization of a novel human sphingosine-1-phosphate phosphohydrolase, hSPP2
[LiteratureReference:428678] Role of human sphingosine-1-phosphate phosphatase 1 in the regulation of intra- and extracellular sphingosine-1-phosphate levels and cell viability
[LiteratureReference:9844177] Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide
modified[InstanceEdit:428698] D'Eustachio, P, 2009-07-06
[InstanceEdit:433040] D'Eustachio, P, 2009-08-20
[InstanceEdit:446904] D'Eustachio, P, 2009-11-18
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:1660664] Jassal, B, 2011-10-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9841787] Stephan, Ralf, 2023-08-12
[InstanceEdit:9843384] Stephan, Ralf, 2023-09-08
[InstanceEdit:9844176] Stephan, Ralf, 2023-09-14
[InstanceEdit:9851294] Stephan, Ralf, 2023-10-20
[InstanceEdit:9851345] Stephan, Ralf, 2023-10-24
[InstanceEdit:9863470] Stephan, Ralf, 2024-02-29
nameSGPP1,2 dephosphorylate sphingoid-1-phosphates
sphinganine 1-phosphate + H2O => sphinganine + orthophosphate
output[SimpleEntity:29372] Pi [cytosol]
[SimpleEntity:428682] SPG [cytosol]
precedingEvent
releaseDate2009-09-30
reviewed[InstanceEdit:446905] Hannun, YA, Luberto, C, 2009-11-18
[InstanceEdit:433039] Jassal, B, 2009-08-20
[InstanceEdit:9851344] D'Eustachio, Peter, 2023-10-24
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105850] R-HSA-428664.5
summation[Summation:428683] SGPP1 and 2 (sphingosine-1-phosphate phosphatase 1 and 2) en...
(hasEvent)[Pathway:9845614] Sphingolipid catabolism [Homo sapiens]
(precedingEvent)[Reaction:428214] SPHK1,SPHK2 phosphorylate sphingoid [Homo sapiens]
(replacementInstances)[_Deleted:9851912] Deletion of instance: 428701
[_Deleted:9852820] Deletion of instance: 428701
[_Deleted:9949971] Deletion of instance: 428701
(updatedInstance)[_UpdateTracker:9853266] Update Tracker - [Reaction:428664] SGPP1,2 dephosphorylate sphingoid-1-phosphates - v87:[addLiteratureReference, add_removeInput, add_removeOutput, modifyText]
[_UpdateTracker:9864000] Update Tracker - [Reaction:428664] SGPP1,2 dephosphorylate sphingoid-1-phosphates - v88:[add_removeCatalystActivity]
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No pathways have been reviewed or authored by SGPP1,2 dephosphorylate sphingoid-1-phosphates (428664)
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