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Details on Person Activation of RAC1 by SOS

Class:IdReaction:428535
_displayNameActivation of RAC1 by SOS
_doReleaseTRUE
_timestamp2017-08-04 19:10:39
authored[InstanceEdit:376175] Garapati, P V, 2008-09-05 06:02:05
catalystActivity[CatalystActivity:428513] guanyl-nucleotide exchange factor activity of SLIT2:ROBO1:NCK:SOS [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:428526] Garapati, P V, 2009-07-06
edited[InstanceEdit:376175] Garapati, P V, 2008-09-05 06:02:05
[InstanceEdit:9010186] Orlic-Milacic, Marija, 2017-06-26
inferredFrom
input[Complex:5674631] RAC1:GDP [plasma membrane] [Homo sapiens]
[SimpleEntity:29438] GTP [cytosol]
modified[InstanceEdit:434967] Garapati, P V, 2009-09-04
[InstanceEdit:500186] Garapati, P V, 2010-02-01
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:8985730] Orlic-Milacic, Marija, 2017-04-20
[InstanceEdit:9010157] Orlic-Milacic, Marija, 2017-06-26
[InstanceEdit:9010187] Orlic-Milacic, Marija, 2017-06-26
[InstanceEdit:9014895] Orlic-Milacic, Marija, 2017-08-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameActivation of RAC1 by SOS
output[Complex:442641] RAC1:GTP [plasma membrane] [Homo sapiens]
[SimpleEntity:29420] GDP [cytosol]
precedingEvent
releaseDate2009-09-30
reviewed[InstanceEdit:434966] Kidd, T, 2009-08-18
[InstanceEdit:9014887] Jaworski, Alexander, 2017-07-31
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104449] R-HSA-428535.4
summation[Summation:428415] SOS (SOS1 or SOS2), bound to Dock orholog NCK (NCK1 or NCK2)...
(hasEvent)[Pathway:428540] Activation of RAC1 [Homo sapiens]
(precedingEvent)[Reaction:428522] Inactivation of RAC1 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9780566] Update Tracker - [Reaction:428535] Activation of RAC1 by SOS - v62:[modifyText]
[_UpdateTracker:9781453] Update Tracker - [Reaction:428535] Activation of RAC1 by SOS - v61:[add_removeInput]
[_UpdateTracker:9790827] Update Tracker - [Reaction:428535] Activation of RAC1 by SOS - v32:[add_removeInput, add_removeOutput]
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No pathways have been reviewed or authored by Activation of RAC1 by SOS (428535)