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Details on Person Inactivation of Cdc42

Class:IdReaction:428519
_displayNameInactivation of Cdc42
_doReleaseTRUE
_timestamp2017-08-04 19:21:22
authored[InstanceEdit:376175] Garapati, P V, 2008-09-05 06:02:05
catalystActivity[CatalystActivity:428512] GTPase activator activity of Robo1:Slit2:SrGAP [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:428526] Garapati, P V, 2009-07-06
edited[InstanceEdit:376175] Garapati, P V, 2008-09-05 06:02:05
[InstanceEdit:9010186] Orlic-Milacic, Marija, 2017-06-26
input[Complex:182921] CDC42:GTP [plasma membrane] [Homo sapiens]
isChimericTRUE
literatureReference[LiteratureReference:428412] Structural basis of Robo proline-rich motif recognition by the srGAP1 Src homology 3 domain in the Slit-Robo signaling pathway
[LiteratureReference:375968] Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway
modified[InstanceEdit:429556] Garapati, P V, 2009-07-16
[InstanceEdit:434971] Garapati, P V, 2009-09-04
[InstanceEdit:500168] Garapati, P V, 2010-02-01
[InstanceEdit:561127] Matthews, L, 2010-03-25
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9010171] Orlic-Milacic, Marija, 2017-06-26
[InstanceEdit:9010187] Orlic-Milacic, Marija, 2017-06-26
[InstanceEdit:9014896] Orlic-Milacic, Marija, 2017-08-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameInactivation of Cdc42
output[SimpleEntity:29372] Pi [cytosol]
[Complex:418830] CDC42:GDP [cytosol] [Homo sapiens]
releaseDate2009-09-30
reviewed[InstanceEdit:434966] Kidd, T, 2009-08-18
[InstanceEdit:9014887] Jaworski, Alexander, 2017-07-31
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48895] Rattus norvegicus
[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104417] R-NUL-428519.3
summation[Summation:9010169] Human SRGAP, bound to the cytoplasmic tail of rat Robo1, inc...
(inferredFrom)[Reaction:428533] Inactivation of CDC42 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9780805] Update Tracker - [Reaction:428519] Inactivation of Cdc42 - v62:[add_removeSummation]
[_UpdateTracker:9791159] Update Tracker - [Reaction:428519] Inactivation of Cdc42 - v32:[add_removeOutput, removeInput]
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No pathways have been reviewed or authored by Inactivation of Cdc42 (428519)