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Details on Person SLIT stimulation recruits SH3-SH2 adaptor protein Dreadlocks...

Class:IdSummation:428424
_displayNameSLIT stimulation recruits SH3-SH2 adaptor protein Dreadlocks...
_timestamp2017-08-04 12:55:32
created[InstanceEdit:428425] Garapati, P V, 2009-07-06
literatureReference[LiteratureReference:428433] Slit stimulation recruits Dock and Pak to the roundabout receptor and increases Rac activity to regulate axon repulsion at the CNS midline
[LiteratureReference:428403] Dock and Pak regulate olfactory axon pathfinding in Drosophila
modified[InstanceEdit:9010157] Orlic-Milacic, Marija, 2017-06-26
[InstanceEdit:9014869] Orlic-Milacic, Marija, 2017-08-04
textSLIT stimulation recruits SH3-SH2 adaptor protein Dreadlocks (Dock) (NCK in vertebrates) to the ROBO1 receptor. This interaction involves the CC2 and CC3 motifs of ROBO1 (Fan et al. 2003, Ang et al. 2003).
(summation)[Reaction:428511] NCK binds ROBO1:SLIT2 [Homo sapiens]
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