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Details on Person SPHK1 and 2 (sphingosine kinases 1 and 2) each catalyze the ...
| Class:Id | Summation:428235 |
|---|---|
| _displayName | SPHK1 and 2 (sphingosine kinases 1 and 2) each catalyze the ... |
| _timestamp | 2020-07-16 13:41:30 |
| created | [InstanceEdit:428277] D'Eustachio, P, 2009-07-03 |
| modified | [InstanceEdit:428280] D'Eustachio, P, 2009-07-03 [InstanceEdit:9695955] Jassal, Bijay, 2020-07-16 |
| text | SPHK1 and 2 (sphingosine kinases 1 and 2) each catalyze the reaction of sphinganine (dihydrosphingosine) and ATP to form dihydrosphingosine 1-phosphate and ADP. Both enzymes are found in the cytosol (although they are also present in membrane-associated forms). Both enzymes also catalyze the phosphorylation of sphingosine to sphingosine 1-phosphate (S1P) (Liu et al. 2000, Nava et al. 2000, Pitson et al. 2000). |
| (summation) | [Reaction:428214] SPHK1,SPHK2 phosphorylate sphingoid [Homo sapiens] |
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No pathways have been reviewed or authored by SPHK1 and 2 (sphingosine kinases 1 and 2) each catalyze the ... (428235)
