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Details on Person GPRK1 phosphorylates metarhodopsin

Class:Id	Reaction:426961
_displayName	GPRK1 phosphorylates metarhodopsin
_doRelease	FALSE
_timestamp	2017-06-27 17:36:03
authored	[InstanceEdit:427137] Williams, MG, 2009-06-16
catalystActivity	[CatalystActivity:427081] protein serine/threonine kinase activity of GPRK1 [rhabdomere membrane]
compartment	[Compartment:263407] rhabdomere membrane
created	[InstanceEdit:426680] Williams, MG, 2009-06-17
figure	[Figure:1014092] /figures/DrosPhotoTransB18.jpg
input	[DefinedSet:426728] Metarhodopsin [rhabdomere membrane] [Drosophila melanogaster] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:426835] Rhodopsin kinase activity modulates the amplitude of the visual response in Drosophila [LiteratureReference:426715] 11-cis-retinal reduces constitutive opsin phosphorylation and improves quantum catch in retinoid-deficient mouse rod photoreceptors [LiteratureReference:426920] Mass spectrometric analysis of the kinetics of in vivo rhodopsin phosphorylation [LiteratureReference:426602] Multiple phosphorylation of rhodopsin and the in vivo chemistry underlying rod photoreceptor dark adaptation
modified	[InstanceEdit:427139] Williams, MG, 2009-06-17 [InstanceEdit:1014203] Williams, MG, 2010-11-12 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9010639] D'Eustachio, Peter, 2017-06-27
name	GPRK1 phosphorylates metarhodopsin
output	[DefinedSet:427118] Phospho Metarhodopsin [rhabdomere membrane] [Drosophila melanogaster] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:426707] Rhodopsin is converted to activated metarhodopsin by light [Drosophila melanogaster] [Reaction:427077] RDGC phosphatase dephosphorylates phosphorylated rhodopsin [Drosophila melanogaster] [Reaction:1014172] Metarhodopsin is converted back to rhodopsin by light [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8890045] R-DME-426961.1
summation	[Summation:427042] The G protein-coupled receptor kinase 1 (GPRK1) protein phos...
(hasEvent)	[Pathway:426741] Formation of Metarhodopsin:Arrestin complex [Drosophila melanogaster]
(precedingEvent)	[Reaction:426924] Arrestin binds to phosphorylated metarhodopsin [Drosophila melanogaster]
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No pathways have been reviewed or authored by GPRK1 phosphorylates metarhodopsin (426961)