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Details on Person Influx of Na+/Ca2+ ions from the extracellular region to the cytosol

Class:Id	Reaction:426668
_displayName	Influx of Na+/Ca2+ ions from the extracellular region to the cytosol
_doRelease	FALSE
_timestamp	2017-06-27 17:36:17
authored	[InstanceEdit:427137] Williams, MG, 2009-06-16
catalystActivity	[CatalystActivity:426811] monoatomic cation channel activity of TRP/L tetramer complex [rhabdomere membrane]
compartment	[Compartment:263407] rhabdomere membrane
created	[InstanceEdit:426680] Williams, MG, 2009-06-17
figure	[Figure:1014083] /figures/DrosPhotoTransB09.jpg
input	[SimpleEntity:74112] Ca2+ [extracellular region] [SimpleEntity:74113] Na+ [extracellular region]
literatureReference	[LiteratureReference:426986] Constitutive activity of the light-sensitive channels TRP and TRPL in the Drosophila diacylglycerol kinase mutant, rdgA [LiteratureReference:426950] Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL
modified	[InstanceEdit:427139] Williams, MG, 2009-06-17 [InstanceEdit:1014204] Williams, MG, 2010-11-12 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9010639] D'Eustachio, Peter, 2017-06-27
name	Influx of Na+/Ca2+ ions from the extracellular region to the cytosol
output	[SimpleEntity:74016] Ca2+ [cytosol] [SimpleEntity:83910] Na+ [cytosol]
precedingEvent	[Reaction:426596] INAE lipase cleaves DAG [Drosophila melanogaster] [Reaction:427020] Activated NORPA cleaves PIP2 [Drosophila melanogaster] [Reaction:426743] LAZA phosphatase dephosphorylates PA [Drosophila melanogaster] [Reaction:427020] Activated NORPA cleaves PIP2 [Drosophila melanogaster] [Reaction:426854] Activated Galpha49B:GTP complex binds to NORPA [Drosophila melanogaster] [Reaction:427069] SKTL kinase phosphorylates PIP [Drosophila melanogaster] [Reaction:426743] LAZA phosphatase dephosphorylates PA [Drosophila melanogaster] [Reaction:426685] RDGA kinase phosphorylates DAG [Drosophila melanogaster] [Reaction:426601] PLD converts PC to PA [Drosophila melanogaster] [Reaction:1014171] TRPL transports from the cell body membrane to the rhabdomere membrane [Drosophila melanogaster] [Reaction:1014183] TRPL transports from the rhabdomere membrane to the cell body membrane [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8913093] R-DME-426668.1
summation	[Summation:427131] DAG (diacylglycerol) or its metabolites PUFA (polyunsaturate...
(hasEvent)	[Pathway:426751] Regulation of Ca2+ ion levels [Drosophila melanogaster]
(precedingEvent)	[Reaction:426979] INAC kinase phosphorylates INAD [Drosophila melanogaster] [Reaction:427099] INAC kinase phosphorylates TRP/L multimer channel [Drosophila melanogaster]
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No pathways have been reviewed or authored by Influx of Na+/Ca2+ ions from the extracellular region to the cytosol (426668)