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Details on Person Nonendonucleolytic RISC binds exactly matching target RNAs

Class:Id	Reaction:426522
_displayName	Nonendonucleolytic RISC binds exactly matching target RNAs
_doRelease	TRUE
_timestamp	2014-02-05 02:41:18
authored	[InstanceEdit:426442] May, B, 2009-06-10
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:426518] May, B, 2009-06-16
edited	[InstanceEdit:426442] May, B, 2009-06-10
input	[OtherEntity:426523] RNA (exact match) [cytosol] [DefinedSet:210807] Nonendonucleolytic RISC [cytosol] [Homo sapiens] [DefinedSet:427775] TNRC6 (GW182) [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:426498] Evidence that microRNAs are associated with translating messenger RNAs in human cells [LiteratureReference:427826] Identification of novel argonaute-associated proteins [LiteratureReference:432331] A role for the P-body component GW182 in microRNA function [LiteratureReference:426507] Molecular basis for target RNA recognition and cleavage by human RISC
modified	[InstanceEdit:426527] May, B, 2009-06-16 [InstanceEdit:427771] May, B, 2009-06-26 [InstanceEdit:427827] May, B, 2009-06-26 [InstanceEdit:432332] May, B, 2009-08-13 [InstanceEdit:541415] May, B, 2010-03-10 [InstanceEdit:629635] May, B, 2010-04-28 [InstanceEdit:772520] May, B, 2010-05-21 [InstanceEdit:847698] May, B, 2010-05-30 [InstanceEdit:1011169] May, B, 2010-11-11 [InstanceEdit:1082223] May, B, 2010-11-29 [InstanceEdit:1216459] May, B, 2011-02-14 [InstanceEdit:1221617] May, B, 2011-02-25 [InstanceEdit:2106631] May, B, 2012-02-10 [InstanceEdit:2106633] May, B, 2012-02-10 [InstanceEdit:5251727] May, B, 2014-02-05 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Nonendonucleolytic RISC binds exactly matching target RNAs
output	[Complex:426510] TNRC6:Nonendonucleolytic RISC:Target RNA (exact match) [cytosol] [Homo sapiens]
precedingEvent	[Reaction:426464] Dicer cleaves double-stranded RNA to yield double-stranded siRNA [Homo sapiens] [Reaction:203862] Dicer cleaves pre-miRNA to yield duplex miRNA [Homo sapiens] [Reaction:203906] Exportin complex translocates pre-miRNA to cytosol [Homo sapiens]
releaseDate	2012-03-13
reviewed	[InstanceEdit:2106616] Tomari, Y, 2012-02-10
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2158054] R-HSA-426522.2
summation	[Summation:426519] RISCs containing Argonaute-1 (AGO1, EIF2C1), AGO3 (EIF2C3), ...
(hasEvent)	[Pathway:426496] Post-transcriptional silencing by small RNAs [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9787134] Update Tracker - [Reaction:426522] Nonendonucleolytic RISC binds exactly matching target RNAs - v46:[modifyText]
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