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Details on Person Endonucleolytic RISC hydrolyzes target RNAs
Class:Id Reaction:426520 _displayName Endonucleolytic RISC hydrolyzes target RNAs _doRelease TRUE _timestamp 2017-09-29 03:06:27 authored [InstanceEdit:426442] May, B, 2009-06-10 catalystActivity [CatalystActivity:426499] RNA endonuclease activity of Endonucleolytic RISC [cytosol] compartment [Compartment:70101] cytosol created [InstanceEdit:426518] May, B, 2009-06-16 edited [InstanceEdit:426442] May, B, 2009-06-10 input [OtherEntity:426523] RNA (exact match) [cytosol] literatureReference [LiteratureReference:426507] Molecular basis for target RNA recognition and cleavage by human RISC [LiteratureReference:426516] A microRNA in a multiple-turnover RNAi enzyme complex [LiteratureReference:426506] Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs [LiteratureReference:210573] Argonaute2 is the catalytic engine of mammalian RNAi [LiteratureReference:427766] Functional Dissection of Human TNRC6, GW182-related, Family of proteins [LiteratureReference:427785] Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs [LiteratureReference:427826] Identification of novel argonaute-associated proteins [LiteratureReference:432337] Purified Argonaute2 and an siRNA form recombinant human RISC [LiteratureReference:6789369] Human Argonaute 2 Has Diverse Reaction Pathways on Target RNAs modified [InstanceEdit:426527] May, B, 2009-06-16 [InstanceEdit:427799] May, B, 2009-06-26 [InstanceEdit:427829] May, B, 2009-06-26 [InstanceEdit:432336] May, B, 2009-08-13 [InstanceEdit:541415] May, B, 2010-03-10 [InstanceEdit:629635] May, B, 2010-04-28 [InstanceEdit:772520] May, B, 2010-05-21 [InstanceEdit:847698] May, B, 2010-05-30 [InstanceEdit:1011169] May, B, 2010-11-11 [InstanceEdit:1082223] May, B, 2010-11-29 [InstanceEdit:1216459] May, B, 2011-02-14 [InstanceEdit:1221617] May, B, 2011-02-25 [InstanceEdit:2106631] May, B, 2012-02-10 [InstanceEdit:2106633] May, B, 2012-02-10 [InstanceEdit:5251727] May, B, 2014-02-05 [InstanceEdit:6789419] May, Bruce, 2015-07-30 [InstanceEdit:9023923] May, Bruce, 2017-09-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name Endonucleolytic RISC hydrolyzes target RNAs output [OtherEntity:426511] Cleaved RNA with 5' Phosphate and 3' Hydroxyl [cytosol] [OtherEntity:426511] Cleaved RNA with 5' Phosphate and 3' Hydroxyl [cytosol] precedingEvent
releaseDate 2012-03-13 reviewed [InstanceEdit:2106616] Tomari, Y, 2012-02-10 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:2158171] R-HSA-426520.4 summation [Summation:426491] Human Argonaute-2 (AGO2, EIF2C2) possesses ribonucleolytic a... (hasEvent) [Pathway:426496] Post-transcriptional silencing by small RNAs [Homo sapiens] (updatedInstance) [_UpdateTracker:9784443] Update Tracker - [Reaction:426520] Endonucleolytic RISC hydrolyzes target RNAs - v54:[addLiteratureReference] [_UpdateTracker:9787207] Update Tracker - [Reaction:426520] Endonucleolytic RISC hydrolyzes target RNAs - v46:[modifyText] [_UpdateTracker:9787435] Update Tracker - [Reaction:426520] Endonucleolytic RISC hydrolyzes target RNAs - v45:[modifyText]
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