Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Diacylglycerol kinases (DGKs) are intracellular lipid kinase...
| Class:Id | Summation:426238 |
|---|---|
| _displayName | Diacylglycerol kinases (DGKs) are intracellular lipid kinase... |
| _timestamp | 2009-06-12 15:55:28 |
| created | [InstanceEdit:426231] Jupe, S, 2009-06-12 |
| literatureReference | [LiteratureReference:426230] Diacylglycerol kinases: at the hub of cell signalling [LiteratureReference:426245] Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells |
| text | Diacylglycerol kinases (DGKs) are intracellular lipid kinases that use ATP to phosphorylate diacylglycerol (DAG)., generating phosphatidic acid (PA). This lowers membrane DAG levels, regulating signalling proteins that require DAG for membrane association such as Protein Kinase C. PA is a signalling molecule that regulates Raf-1 and PKC zeta, and a substrate for the resynthesis of phosphatidylinositol. |
| (summation) | [Reaction:426240] DAG kinase produces phosphatidic acid from DAG [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Diacylglycerol kinases (DGKs) are intracellular lipid kinase... (426238)
