Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:Q9BQK8-1 LPIN3
| Class:Id | ReferenceIsoform:424845 |
|---|---|
| _chainChangeLog | chain:1-851 added on Fri February 6 2015 |
| _displayName | UniProt:Q9BQK8-1 LPIN3 |
| _timestamp | 2024-11-03 20:06:03 |
| chain | chain:1-851 |
| checksum | BBDFDA0A53722625 |
| comment | FUNCTION Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis therefore regulates fatty acid metabolism.CATALYTIC ACTIVITY a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphateCOFACTOR Inhibited by N-ethylmaleimide.SUBCELLULAR LOCATION Significant expression in intestine and other regions of the gastrointestinal tract.DOMAIN Contains 1 Asp-Xaa-Asp-Xaa-Thr (DXDXT) motif, a catalytic motif known to be essential for phosphatidate phosphatase activity.DOMAIN Contains one Leu-Xaa-Xaa-Ile-Leu (LXXIL) motif, a motif known to be a transcriptional binding motif.SIMILARITY Belongs to the lipin family. |
| created | [InstanceEdit:423310] Kanapin, AA |
| description | recommendedName: fullName evidence="7"Phosphatidate phosphatase LPIN3 ecNumber evidence="2"3.1.3.4 alternativeName: Lipin-3 alternativeName: Lipin-3-like |
| geneName | LPIN3 LIPN3L |
| identifier | Q9BQK8 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Fatty acid metabolism Hydrolase Lipid metabolism Nucleus Phosphoprotein Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | LPIN3 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8994916] ENSEMBL:ENSG00000132793 LPIN3 [Homo sapiens] |
| secondaryIdentifier | LPIN3_HUMAN B2RTT5 Q5TDB9 Q9NPY8 Q9UJE5 |
| sequenceLength | 851 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | Q9BQK8-1 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9BQK8-1 LPIN3 (424845)
