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Details on Person ROCK1 phosphorylates LIMK2 (rat)

Class:Id	Reaction:421733
_displayName	ROCK1 phosphorylates LIMK2 (rat)
_doRelease	TRUE
_timestamp	2015-01-28 18:30:22
authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
catalystActivity	[CatalystActivity:420678] protein serine/threonine kinase activity of ROCK1 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:421732] Jupe, S, 2009-05-20 11:58:07
edited	[InstanceEdit:421729] Jupe, S, 2009-05-20 11:38:59
input	[SimpleEntity:113592] ATP [cytosol] [EntityWithAccessionedSequence:421731] Limk2 [cytosol] [Rattus norvegicus]
isChimeric	TRUE
literatureReference	[LiteratureReference:420676] Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase
modified	[InstanceEdit:421738] Jupe, S, 2009-05-20 12:07:46 [InstanceEdit:422117] Garapati, P V, 2009-05-26 10:26:49 [InstanceEdit:422119] Garapati, P V, 2009-05-26 10:52:13 [InstanceEdit:425220] Jupe, S, 2009-06-03 [InstanceEdit:425237] Garapati, P V, 2009-06-03 [InstanceEdit:425946] Garapati, P V, 2009-06-09 [InstanceEdit:427480] Jupe, S, 2009-06-22 [InstanceEdit:435044] Garapati, P V, 2009-09-05 [InstanceEdit:561126] Matthews, L, 2010-03-25 [InstanceEdit:4640897] Garapati, P V, 2013-09-27 [InstanceEdit:5668845] Orlic-Milacic, Marija, 2015-01-28 [InstanceEdit:5668850] Orlic-Milacic, Marija, 2015-01-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ROCK1 phosphorylates LIMK2 (rat)
output	[SimpleEntity:29370] ADP [cytosol] [EntityWithAccessionedSequence:421736] p-T505-Limk2 [cytosol] [Rattus norvegicus]
releaseDate	2009-09-30
reviewed	[InstanceEdit:434621] Kumanogoh, A, Kikutani, H, 2009-09-01 [InstanceEdit:5668821] Rivero Crespo, Francisco, 2014-12-26
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:5668845] Orlic-Milacic, Marija, 2015-01-28
species	[Species:48887] Homo sapiens [Species:48895] Rattus norvegicus
stableIdentifier	[StableIdentifier:1104813] R-NUL-421733.2
summation	[Summation:5668843] ROCK-mediated phosphorylation of LIM kinase 2 at threonine r...
(inferredFrom)	[Reaction:419087] LIM kinase phosphorylation by ROCK [Homo sapiens] [Reaction:3928577] ROCK phosphorylates LIMK1,2 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9785215] Update Tracker - [Reaction:421733] ROCK1 phosphorylates LIMK2 (rat) - v52:[add_removeSummation, removeLiteratureReference] [_UpdateTracker:9785714] Update Tracker - [Reaction:421733] ROCK1 phosphorylates LIMK2 (rat) - v51:[modifyText] [_UpdateTracker:9786937] Update Tracker - [Reaction:421733] ROCK1 phosphorylates LIMK2 (rat) - v47:[modifyText]
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