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Details on Person Formation of PPAT dimers

Class:Id	Reaction:420911
_displayName	Formation of PPAT dimers
_doRelease	TRUE
_timestamp	2016-11-10 00:57:12
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:420913] D'Eustachio, P, 2009-05-14 17:32:05
inferredFrom	[Reaction:111289] Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer [Homo sapiens]
input	[Complex:420903] PPAT tetramer [cytosol] [Gallus gallus]
literatureReference	[LiteratureReference:420910] Glutamine phosphoribosylpyrophosphate amidotransferase. Catalytic and conformational heterogeneity of the pigeon liver enzyme [LiteratureReference:111231] Human glutamine phosphoribosylpyrophosphate amidotransferase. Two molecular forms interconvertible by purine ribonucleotides and phosphoribosylpyrophosphate [LiteratureReference:420914] Phosphoribosyl pyrophosphate amidotransferase. Purification and general catalytic properties [LiteratureReference:420909] The enzymology of feedback inhibition of glutamine phosphoribosylpyrophosphate amidotransferase by purine ribonucleotides
modified	[InstanceEdit:420917] D'Eustachio, P, 2009-05-14 17:32:15 [InstanceEdit:1660613] D'Eustachio, P, 2011-10-13 [InstanceEdit:1667320] D'Eustachio, P, 2011-10-14 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of PPAT dimers
output	[Complex:420912] PPAT dimer [cytosol] [Gallus gallus] [Complex:420912] PPAT dimer [cytosol] [Gallus gallus]
regulatedBy	[NegativeRegulation:420918] Negative regulation by 'guanosine 5'-monophosphate [cytosol]' [PositiveRegulation:420919] Positive regulation by 'PRPP [cytosol]' [NegativeRegulation:420920] Negative regulation by 'adenosine 5'-monophosphate [cytosol]' [NegativeRegulation:1667636] Negative regulation by 'IMP [cytosol]'
releaseDate	2008-09-30
reverseReaction	[Reaction:420906] Formation of PPAT tetramers [Gallus gallus] [Reaction:420911] Formation of PPAT dimers [Gallus gallus]
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:2016596] R-GGA-420911.4
summation	[Summation:420904] Biochemical characterization of purified avian PPAT (chicken...
(hasEvent)	[Pathway:419140] De novo synthesis of IMP [Gallus gallus]
(precedingEvent)	[Reaction:419152] 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate [Gallus gallus]
(reverseReaction)	[Reaction:420906] Formation of PPAT tetramers [Gallus gallus]
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No pathways have been reviewed or authored by Formation of PPAT dimers (420911)