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Details on Person Biochemical characterization of purified avian PPAT (chicken...
| Class:Id | Summation:420904 |
|---|---|
| _displayName | Biochemical characterization of purified avian PPAT (chicken... |
| _timestamp | 2009-05-14 17:32:16 |
| created | [InstanceEdit:420913] D'Eustachio, P, 2009-05-14 17:32:05 |
| modified | [InstanceEdit:420917] D'Eustachio, P, 2009-05-14 17:32:15 |
| text | Biochemical characterization of purified avian PPAT (chicken (Hartman 1963) and pigeon (Caskey et al. 1964; Rowe et al. 1970)) suggest that while both PPAT dimers and tetramers are catalytically active in vitro, PPRP allosterically activates PPAT while AMP and GMP allosterically inactivate it, and activity changes are associated with changes in enzyme multimerization. The specific reaction annotated here, dissociation of relatively inactive PPAT tetramers to form active dimers, its stimulation by PRPP, and its inhibition by AMP and GMP, are inferred from studies of the homologous human enzyme (Holmes et al. 1973). |
| (summation) | [Reaction:420911] Formation of PPAT dimers [Gallus gallus] |
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No pathways have been reviewed or authored by Biochemical characterization of purified avian PPAT (chicken... (420904)
