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Details on Person The adrenomedullin receptor can bind adrenomedullin and intermedin

Class:IdReaction:420214
_displayNameThe adrenomedullin receptor can bind adrenomedullin and intermedin
_doReleaseTRUE
_timestamp2010-12-02 14:33:41
authored[InstanceEdit:420077] Jassal, Bijay, 2009-05-11
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:420077] Jassal, Bijay, 2009-05-11
edited[InstanceEdit:420077] Jassal, Bijay, 2009-05-11
input[DefinedSet:420061] ADM,ADM2 [extracellular region] [Homo sapiens]
[DefinedSet:420118] Adrenomedullin receptor [plasma membrane] [Homo sapiens]
literatureReference[LiteratureReference:420222] Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes
[LiteratureReference:419827] Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma
[LiteratureReference:420138] The RAMP2/CRLR complex is a functional adrenomedullin receptor in human endothelial and vascular smooth muscle cells
[LiteratureReference:420195] Receptor activity modifying proteins interaction with human and porcine calcitonin receptor-like receptor (CRLR) in HEK-293 cells
[LiteratureReference:420203] RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
modified[InstanceEdit:420852] Jassal, Bijay, 2009-05-14
[InstanceEdit:420853] Jassal, Bijay, 2009-05-14
[InstanceEdit:422124] Jassal, Bijay, 2009-05-26
[InstanceEdit:422353] Jassal, Bijay, 2009-05-28
[InstanceEdit:422382] Jassal, Bijay, 2009-05-29
[InstanceEdit:532503] Jupe, S, 2010-03-01
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameThe adrenomedullin receptor can bind adrenomedullin and intermedin
output[Complex:420062] Adrenomedullin receptor:ADM,ADM2 [plasma membrane] [Homo sapiens]
releaseDate2009-06-24
reviewed[InstanceEdit:422381] D'Eustachio, P, 2009-05-29 07:44:22
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104383] R-HSA-420214.2
summation[Summation:420231] Intermedin (AM2) (Roh J et al, 2004) and adrenomedullin (AM)...
(hasEvent)[Pathway:419812] Calcitonin-like ligand receptors [Homo sapiens]
(precedingEvent)[Reaction:744887] Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs [Homo sapiens]
[Reaction:9660828] ADORA2B:Ade-Rib binds heterometric G-protein Gs [Homo sapiens]
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