Query author contributions in Reactome
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Details on Person The pituitary adenylate cyclase-activating peptide (PACAP) (...
| Class:Id | Summation:420168 |
|---|---|
| _displayName | The pituitary adenylate cyclase-activating peptide (PACAP) (... |
| _timestamp | 2009-05-11 13:37:43 |
| created | [InstanceEdit:420077] Jassal, Bijay, 2009-05-11 |
| text | The pituitary adenylate cyclase-activating peptide (PACAP) (Ohkubo S et al, 1992) is a peptide hormone similar to vasoactive intestinal peptide (VIP). PACAP functions as a hypophysiotropic hormone, neurotransmitter and neuromodulator. Three active peptides are cleaved from the precursor protein; PACAP-related peptide, PACAP-27 and PACAP-38. The effects of the PACAP peptides are mediated by the PACAP receptor (Ogi K et al, 1993). This receptor is predominantly expressed in the CNS. The activity of the receptor is mediated by coupling with the G protein alpha s subunit, which stimulates adenylyl cyclase which increases intracellular cAMP levels (Ogi K et al, 1993). |
| (summation) | [Reaction:420131] The PACAP receptor binds PACAP [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The pituitary adenylate cyclase-activating peptide (PACAP) (... (420168)
