Reactome: A Curated Pathway Database
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Details on Person PAR-3 binds to junctional adhesion molecules JAM-A, -B, and ...

Class:IdSummation:419986
_displayNamePAR-3 binds to junctional adhesion molecules JAM-A, -B, and ...
_timestamp2009-05-11 02:27:33
created[InstanceEdit:420013] Matthews, L, 2009-05-10 20:37:01
literatureReference[LiteratureReference:419982] The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity
[LiteratureReference:419972] The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)
modified[InstanceEdit:420038] Matthews, L, 2009-05-11 02:26:47
textPAR-3 binds to junctional adhesion molecules JAM-A, -B, and -C (Ebnet et al. 2001, 2003). The interaction with JAM-A may anchor the PAR-3:PAR-6–aPKC complex to tight junctions. The PAR complex appears to play a critical role in tight junction formation (reviewed in Ebnet, 2008).
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