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Details on Person (S)-dihydroorotate + ubiquinone => orotate + ubiquinol

Class:Id	Reaction:419452
_displayName	(S)-dihydroorotate + ubiquinone => orotate + ubiquinol
_doRelease	TRUE
_timestamp	2016-11-10 00:55:32
authored	[InstanceEdit:419450] D'Eustachio, P, 2009-05-01 14:10:50
catalystActivity	[CatalystActivity:419459] dihydroorotate dehydrogenase activity of DHODH holoenzyme [mitochondrial inner membrane]
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:70101] cytosol
created	[InstanceEdit:419463] D'Eustachio, P, 2009-05-01 14:29:27
edited	[InstanceEdit:419450] D'Eustachio, P, 2009-05-01 14:10:50
inferredFrom	[Reaction:73569] DHODH:FMN oxidises (S)-DHO to orotate [Homo sapiens]
input	[SimpleEntity:76630] (S)-DHO [cytosol] [SimpleEntity:73663] CoQ [mitochondrial inner membrane]
modified	[InstanceEdit:419468] D'Eustachio, P, 2009-05-01 14:29:40 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:1660613] D'Eustachio, P, 2011-10-13 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	(S)-dihydroorotate + ubiquinone => orotate + ubiquinol
output	[SimpleEntity:76632] ORO [cytosol] [SimpleEntity:76633] QH2 [mitochondrial inner membrane]
precedingEvent	[Reaction:419465] N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O [Gallus gallus] [Reaction:419451] carbamoyl phosphate + L-aspartate <=> N-carbamoyl L-aspartate + orthophosphate [Gallus gallus]
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:2016641] R-GGA-419452.3
summation	[Summation:419455] Dihydroorotate dehydrogenase catalyzes the oxidation of dihy...
(hasEvent)	[Pathway:419469] Pyrimidine metabolism: de novo synthesis of UMP [Gallus gallus]
(precedingEvent)	[Reaction:419462] orotate + 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) <=> orotidine 5'-monophosphate (OMP) + pyrophosphate [Gallus gallus]
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No pathways have been reviewed or authored by (S)-dihydroorotate + ubiquinone => orotate + ubiquinol (419452)