Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Platelet-activating factor (PAF, AGEPC, acetyl-glyceryl-ethe...
| Class:Id | Summation:419388 |
|---|---|
| _displayName | Platelet-activating factor (PAF, AGEPC, acetyl-glyceryl-ethe... |
| _timestamp | 2009-04-30 13:40:27 |
| created | [InstanceEdit:419301] Jassal, Bijay, 2009-04-30 |
| text | Platelet-activating factor (PAF, AGEPC, acetyl-glyceryl-ether-phosphorylcholine) is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis. It is an important mediator of bronchoconstriction. It causes platelets to aggregate and blood vessels to dilate so is important to the process of hemostasis. The PAF receptor (Ye RD et al, 1991) shows structural characteristics of the rhodopsin gene family and binds platelet-activating factor (PAF). The activity of this receptor is mediated by coupling with the G protein alpha q subunit which stimulates PLC-beta which can cleave PIP2 to form secondary messengers (Deo DD et al, 2004). |
| (summation) | [Reaction:419351] PAF receptor binds platelet activating factor [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Platelet-activating factor (PAF, AGEPC, acetyl-glyceryl-ethe... (419388)
