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Details on Person The phosphoribosylaminoimidazolecarboxamide formyltransferas...
| Class:Id | Summation:419251 |
|---|---|
| _displayName | The phosphoribosylaminoimidazolecarboxamide formyltransferas... |
| _timestamp | 2009-04-29 19:22:49 |
| created | [InstanceEdit:419263] D'Eustachio, P, 2009-04-29 19:22:36 |
| modified | [InstanceEdit:419265] D'Eustachio, P, 2009-04-29 19:22:50 |
| text | The phosphoribosylaminoimidazolecarboxamide formyltransferase activity of cytosolic ATIC (bifunctional purine biosynthesis protein PURH) catalyzes the reaction of 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) and 10-formyltetrahydrofolate to form 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) and tetrahydrofolate. The chicken protein has been purified and characterized biochemically (Muellerand Benkovic 1981); structural studies indicate that it occurs as a homodimer (Greasley et al. 2001). |
| (summation) | [Reaction:419254] 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + 10-formyltetrahydrofolate => 5'-phosphoribosyl-5-formaminoimidazole-4-carboxamide (FAICAR) + tetrahydrofolate [Gallus gallus] |
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