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Details on Person Myosin phosphatase dephosphorylates myosin regulatory light chain

Class:IdReaction:419232
_displayNameMyosin phosphatase dephosphorylates myosin regulatory light chain
_doReleaseTRUE
_timestamp2017-03-15 17:40:35
authored[InstanceEdit:425201] Akkerman, JW, 2009-06-03
catalystActivity[CatalystActivity:419228] myosin-light-chain-phosphatase activity of Myosin phosphatase [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:419231] Jupe, S, 2009-04-29 15:19:56
edited[InstanceEdit:5668853] Orlic-Milacic, Marija, 2015-01-28
inferredFrom
input[Complex:419195] p-T19,S20-MRLC-smooth muscle/non-muscle myosin II [cytosol] [Homo sapiens]
[SimpleEntity:29356] H2O [cytosol]
literatureReference[LiteratureReference:5668814] Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
[LiteratureReference:5668870] Rho-kinase--mediated contraction of isolated stress fibers
[LiteratureReference:5668869] Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells
[LiteratureReference:5668864] Regulation of myosin phosphatase through phosphorylation of the myosin-binding subunit in platelet activation
modified[InstanceEdit:419588] Jupe, S, 2009-05-05 12:12:08
[InstanceEdit:420637] Jupe, S, 2009-05-12 16:42:21
[InstanceEdit:420651] Jupe, S, 2009-05-12 17:11:59
[InstanceEdit:421624] Jupe, S, 2009-05-19 12:01:27
[InstanceEdit:421637] Jupe, S, 2009-05-19 12:17:55
[InstanceEdit:435398] Jupe, S, 2009-09-09
[InstanceEdit:5668875] Orlic-Milacic, Marija, 2015-01-28
[InstanceEdit:5674244] Orlic-Milacic, Marija, 2015-02-11
[InstanceEdit:5674554] Orlic-Milacic, Marija, 2015-02-12
[InstanceEdit:8981921] Orlic-Milacic, Marija, 2017-03-15
[InstanceEdit:8982008] Orlic-Milacic, Marija, 2017-03-15
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMyosin phosphatase dephosphorylates myosin regulatory light chain
output[Complex:419194] Smooth muscle/non-muscle myosin II [cytosol] [Homo sapiens]
[SimpleEntity:29372] Pi [cytosol]
precedingEvent
regulatedBy[NegativeRegulation:8981999] Negative regulation by 'p-S144,T423-PAK1 [cytosol]'
releaseDate2015-03-19
reviewed[InstanceEdit:5668821] Rivero Crespo, Francisco, 2014-12-26
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5668853] Orlic-Milacic, Marija, 2015-01-28
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5680030] R-HSA-419232.4
summation[Summation:419230] In non-muscle cells, phosphorylation of myosin II regulates ...
(hasEvent)[Pathway:419233] Cytoskeletal regulation [Homo sapiens]
[Pathway:5625740] RHO GTPases activate PKNs [Homo sapiens]
[Pathway:5627117] RHO GTPases Activate ROCKs [Homo sapiens]
[Pathway:5627123] RHO GTPases activate PAKs [Homo sapiens]
(updatedInstance)[_UpdateTracker:9781151] Update Tracker - [Reaction:419232] Myosin phosphatase dephosphorylates myosin regulatory light chain - v61:[addRegulator]
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No pathways have been reviewed or authored by Myosin phosphatase dephosphorylates myosin regulatory light chain (419232)
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