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Details on Person 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate

Class:IdReaction:419152
_displayName5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate
_doReleaseTRUE
_timestamp2016-11-10 00:54:48
authored[InstanceEdit:419262] D'Eustachio, P, 2009-04-29 19:20:17
catalystActivity[CatalystActivity:419135] amidophosphoribosyltransferase activity of PPAT dimer [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:419136] D'Eustachio, P, 2009-04-28 21:22:12
edited[InstanceEdit:419262] D'Eustachio, P, 2009-04-29 19:20:17
input[SimpleEntity:73566] PRPP [cytosol]
[SimpleEntity:29472] L-Gln [cytosol]
[SimpleEntity:29356] H2O [cytosol]
literatureReference[LiteratureReference:419150] Cloning and expression of avian glutamine phosphoribosylpyrophosphate amidotransferase. Conservation of a bacterial propeptide sequence supports a role for posttranslational processing
[LiteratureReference:420914] Phosphoribosyl pyrophosphate amidotransferase. Purification and general catalytic properties
modified[InstanceEdit:419263] D'Eustachio, P, 2009-04-29 19:22:36
[InstanceEdit:420913] D'Eustachio, P, 2009-05-14 17:32:05
[InstanceEdit:1660613] D'Eustachio, P, 2011-10-13
[InstanceEdit:1667320] D'Eustachio, P, 2011-10-14
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate
output[SimpleEntity:111292] PRA [cytosol]
[SimpleEntity:29404] L-Glu [cytosol]
[SimpleEntity:111294] PPi [cytosol]
precedingEvent
releaseDate2008-09-30
reviewStatus[ReviewStatus:9821382] five stars
species[Species:49591] Gallus gallus
stableIdentifier[StableIdentifier:2016660] R-GGA-419152.3
summation[Summation:419154] Cytosolic PPAT (phosphoribosyl pyrophosphate amidotransferas...
(hasEvent)[Pathway:419140] De novo synthesis of IMP [Gallus gallus]
(precedingEvent)[Reaction:419153] 5-phosphoribosylamine + glycine + ATP <=> 5-phosphoribosylglycinamide (GAR) + adenosine 5'-diphosphate + orthophosphate [Gallus gallus]
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No pathways have been reviewed or authored by 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate + pyrophosphate (419152)