Query author contributions in Reactome
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Details on Person Rho-associated, coiled-coil containing protein kinases (ROCK...
| Class:Id | Summation:419062 |
|---|---|
| _displayName | Rho-associated, coiled-coil containing protein kinases (ROCK... |
| _timestamp | 2009-06-03 17:32:32 |
| created | [InstanceEdit:419048] Jupe, S, 2009-04-28 12:51:40 |
| literatureReference | [LiteratureReference:419067] Rocks: multifunctional kinases in cell behaviour [LiteratureReference:425331] Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho [LiteratureReference:421378] The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase |
| modified | [InstanceEdit:425330] Jupe, S, 2009-06-03 |
| text | Rho-associated, coiled-coil containing protein kinases (ROCKs) are downstream effectors of Rho. Rho binding releases an autoinhibitoy loop within ROCK allowing catalytic activity. Multiple targets of ROCK contribute to the stabilization of actin filaments and the generation of actin-myosin contractile force. |
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No pathways have been reviewed or authored by Rho-associated, coiled-coil containing protein kinases (ROCK... (419062)
