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Details on Person Recruitment and activation of N-WASP by Cdc42

Class:IdReaction:418874
_displayNameRecruitment and activation of N-WASP by Cdc42
_doReleaseTRUE
_timestamp2010-12-02 14:35:38
authored[InstanceEdit:373757] Garapati, P V, 2008-07-16 14:42:16
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:418861] Garapati, P V, 2009-04-27 09:27:02
edited[InstanceEdit:374705] Garapati, P V, 2008-07-30 10:24:23
input[Complex:418820] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:201873] N-WASP [cytosol] [Homo sapiens]
[SimpleEntity:179856] PI(4,5)P2 [plasma membrane]
literatureReference[LiteratureReference:418750] Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex
[LiteratureReference:202984] Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate
modified[InstanceEdit:422010] Garapati, P V, 2009-05-25 19:40:44
[InstanceEdit:425946] Garapati, P V, 2009-06-09
[InstanceEdit:446620] Garapati, P V, 2009-11-15
[InstanceEdit:448356] Garapati, P V, 2009-11-24
[InstanceEdit:513007] Garapati, P V, 2010-02-16
[InstanceEdit:532573] Garapati, P V, 2010-03-01
[InstanceEdit:763358] Garapati, P V, 2010-05-20
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRecruitment and activation of N-WASP by Cdc42
output[Complex:418834] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP:WASL:PIP2 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2010-06-15
reviewed[InstanceEdit:513006] Cooper, HM, 2010-02-16
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104736] R-HSA-418874.2
summation[Summation:418738] The adaptor protein Nck-1 binds to DCC and recruits Rac-1, C...
(hasEvent)[Pathway:418885] DCC mediated attractive signaling [Homo sapiens]
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