Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person DCC interacts directly with PITPalpha and this interaction i...
| Class:Id | Summation:418687 |
|---|---|
| _displayName | DCC interacts directly with PITPalpha and this interaction i... |
| _timestamp | 2010-04-23 13:17:08 |
| created | [InstanceEdit:418674] Garapati, P V, 2009-04-27 08:46:46 |
| literatureReference | [LiteratureReference:418693] DCC-dependent phospholipase C signaling in netrin-1-induced neurite elongation [LiteratureReference:418683] Phosphatidylinositol transfer protein-alpha in netrin-1-induced PLC signalling and neurite outgrowth |
| modified | [InstanceEdit:593699] Garapati, P V, 2010-04-13 [InstanceEdit:622377] Garapati, P V, 2010-04-23 |
| text | DCC interacts directly with PITPalpha and this interaction is enhanced in the presence of Netrin-1. The interaction of DCC with PITPalpha requires the carboxy-terminal dmain of both the proteins. PITPalpha signaling pathway is important for netrin-1 mediated axon outgrowth. Netrin-1 activates PITPalpha to regulate local phosphoinositide (PI) synthesis, which is important for PI3K dependent neurite elongation. |
| (summation) | [Reaction:418866] PITPalpha binds DCC [Homo sapiens] [Reaction:593695] PITPalpha binds DCC [Mus musculus] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by DCC interacts directly with PITPalpha and this interaction i... (418687)
