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Details on Person PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release

Class:IdReaction:418442
_displayNamePKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release
_doReleaseTRUE
_timestamp2010-12-02 14:34:45
authored[InstanceEdit:425201] Akkerman, JW, 2009-06-03
catalystActivity[CatalystActivity:418433] cGMP-dependent protein kinase activity of Cyclic GMP-dependent protein kinases (PKGs) [cytosol]
compartment[Compartment:70101] cytosol
[Compartment:114521] platelet dense tubular network membrane
created[InstanceEdit:418443] Jupe, S, 2009-04-22 15:43:52
edited[InstanceEdit:870305] Jupe, S, 2010-06-07
input[Complex:418425] IRAG:ITPR1 [platelet dense tubular network membrane] [Homo sapiens]
literatureReference[LiteratureReference:418447] IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation
modified[InstanceEdit:418565] Jupe, S, 2009-04-23 15:40:54
[InstanceEdit:418588] Jupe, S, 2009-04-24 10:09:48
[InstanceEdit:427873] Jupe, S, 2009-06-29
[InstanceEdit:435204] Jupe, S, 2009-09-07
[InstanceEdit:870306] Jupe, S, 2010-06-07
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release
output[Complex:418432] Phosphorylated IRAG:IP3 receptor type 1 [platelet dense tubular network membrane] [Homo sapiens]
precedingEvent
releaseDate2010-09-21
reviewed[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104578] R-HSA-418442.2
summation[Summation:418444] IRAG, PKG1(cGKI), and IP3 receptor type 1 can be isolated as...
(hasEvent)[Pathway:418457] cGMP effects [Homo sapiens]
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