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Details on Person F2R:ARRB1 binds MAPKs, SRC-1

Class:IdReaction:418170
_displayNameF2R:ARRB1 binds MAPKs, SRC-1
_doReleaseTRUE
_timestamp2020-12-02 14:22:04
authored[InstanceEdit:425201] Akkerman, JW, 2009-06-03
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:418171] Jupe, S, 2009-04-16 15:29:14
edited[InstanceEdit:870306] Jupe, S, 2010-06-07
input[Complex:418080] F2R:ARRB1 [plasma membrane] [Homo sapiens]
[DefinedSet:169291] MAPKs [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:354153] SRC-1 [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:418092] Opposing effects of beta-arrestin1 and beta-arrestin2 on activation and degradation of Src induced by protease-activated receptor 1
[LiteratureReference:418153] Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes
modified[InstanceEdit:418174] Jupe, S, 2009-04-16 15:38:46
[InstanceEdit:428744] Jupe, S, 2009-07-08
[InstanceEdit:435397] Jupe, S, 2009-09-09
[InstanceEdit:456920] Jupe, S, 2010-01-22
[InstanceEdit:870420] Jupe, S, 2010-06-08
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9708864] Jassal, Bijay, 2020-12-02
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameF2R:ARRB1 binds MAPKs, SRC-1
Beta-arrestin-1 acts as scaffold for a PAR1 signalling complex
output[Complex:418103] F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2010-09-21
reviewed[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104949] R-HSA-418170.3
summation[Summation:418175] Beta-arrestins can serve as scaffolding molecules that facil...
(hasEvent)[Pathway:456926] Thrombin signalling through proteinase activated receptors (PARs) [Homo sapiens]
(precedingEvent)[BlackBoxEvent:418158] SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) [Homo sapiens]
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No pathways have been reviewed or authored by F2R:ARRB1 binds MAPKs, SRC-1 (418170)