Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person The full composition and order of assembly of the Heterochro...

Class:IdSummation:417211
_displayNameThe full composition and order of assembly of the Heterochro...
_timestamp2009-06-25 19:47:12
created[InstanceEdit:417212] May, B, 2009-04-12 08:46:12
modified[InstanceEdit:417256] May, B, 2009-04-12 09:06:30
[InstanceEdit:427751] May, B, 2009-06-25
textThe full composition and order of assembly of the Heterochromatic Chromatin Replication complex are incompletely known. It is possible that the complex changes composition as S-phase progresses and different chromatin domains are traversed. The following direct protein-protein interactions have been demonstrated:
DNMT1 - DMAP1
UHRF1(NP95) - DNMT1
DNMT1 - PCNA
CAF1 - PCNA
CAF1 - MBD1
HDAC1 - PCNA
HDAC1 - DNMT1
WSTF - SNF2H
WSTF - PCNA
HDAC2 - DNMT1
ASF1 - CAF1
In addition, UHRF1(NP95) and MBD1 bind methylated cytosine in DNA.
(summation)[Complex:212082] Heterochromatin Replication Complex [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by The full composition and order of assembly of the Heterochro... (417211)